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Treatment of Depression in Nursing Homes



Treatment of Depression in Nursing Homes

For Condition: Major Depressive Disorder,Depression
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to implement an effective treatment for depression in the nursing home setting.
Details: Depression in long-term care facilities is a significant public health issue. Up to 50% of nursing home residents are affected by significant depressive symptoms. The decreased health and limited cognitive ability of many nursing home residents makes treatment and research extremely challenging. This study will attempt to identify and implement treatments for depressed nursing home residents. Participants are randomly assigned to receive either an active intervention or treatment as usual for 6 weeks. The active intervention is followed by 4 weeks of maintenance. The intervention is implemented primarily by existing nursing facility staff and focuses on increasing opportunities for residents to experience pleasant events through increased levels of activity and positive affect. The maintenance treatment involves incorporation of protocol-based activities into patient care plans. Patients have a follow-up visit 12 weeks after the study. Psychiatric evaluations, depression and mood rating scales, observed affect and activity participation, behavior problems, and staff burden are assessed.
Eligibility:
Study Type:  Interventional, Educational/Counseling/Training, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 60 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Nursing home residents - DSM-IV criteria for major depressive disorder or dysthymia or Research Diagnostic Criteria for minor depressive disorder with current Geriatric Depression Scale scores > 11 and Mini Mental State scores >= 14
Total Enrollment: 40

Location and Contact Information:

Overall Study Official:
SuzanneMeeks,  Principal Investigator,  University of Louisville

University of Louisville *Recruiting*
Louisville,  Kentucky,  40292
United States
Recruiting Suzanne  Meeks 502-852-6068


Additional Information:
Study ID Numbers:  63073-01A1; 
Study Start Date: April 2002
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00056485

Other Major Depressive Disorder Studies:
1. Duloxetine vs. active comparator in the treatment of patients with depression

2. Sertraline for Alcohol Dependence and Depression

3. Reducing Depression in Caregivers to People with Dementia

4. Prevention of Suicide in the Elderly

5. Drug Therapy to Treat Minor Depression

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