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Treatment of Depression After Coronary Bypass Surgery Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified medical advice, calls or professional assistance using a genuine dr.. We aren't physicians. Always confer with your dr. on Treatment of Depression After Coronary Bypass Surgery conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Treatment of Depression After Coronary Bypass Surgery Clinical research trials and Treatment of Depression After Coronary Bypass Surgery medical trials happen in hundreds of localities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new does drugs. The intent of the studies / undertakings is to answer particular human health questions. Clinical trials are a popular manner for physicians, government agencies, and private sector corporations to find cures for all kinds of circumstances, like Treatment of Depression After Coronary Bypass Surgery. Treatment of Depression After Coronary Bypass Surgery Clinical Trials and other clinical trials permit volunteers to acquire healthcare treatment options before they are available to the general public. Some times the subjects acquire professional assistance for free, and sometimes they are paid for their time. Sometimes there is a cost for a Treatment of Depression After Coronary Bypass Surgery clinical trial. Participants frequently obtain the most expert healthcare available for their Treatment of Depression After Coronary Bypass Surgery condition. Dangers are a reality, nevertheless, and can include more or frequent doctor calls, health risks (potentially life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
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Home > "T" Clinical Trials Conditions > Treatment of Depression After Coronary Bypass Surgery  Treatment of Depression After Coronary Bypass Surgery
Treatment of Depression After Coronary Bypass Surgery
For Condition: Depressive Disorder,Coronary Disease
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to test the efficacy of cognitive behavior therapy (CBT) and stress management (SM) therapy as treatments for depression in people who have recently undergone coronary artery bypass graft (CABG) surgery.
Details: Depression is a very common problem for people who have had CABG surgery. It is associated with concentration and memory problems, and recent studies have shown that it may increase the risk of additional medical problems and death during the first few years after surgery. Both CBT and SM therapy have been shown to be effective in the treatment of depression in otherwise healthy individuals. These therapies have not, however, been tested for depression in individuals who have undergone CABG surgery. Participants are screened for depression 4 to 6 weeks after surgery. Those who have depression return for additional testing 1 week later. Patients are then randomized to receive CBT, SM, or usual care (with no restriction on nonstudy antidepressants) for 12 weeks. Patients are monitored for worsening depression and are referred for additional care if needed. Depression outcomes, which include daily activities, concentration and memory, and quality of life, are assessed 12 weeks after randomization and 6 months after surgery (2 months after termination of CBT or SM).
Eligibility:
Study Type: Interventional, Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 21 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Coronary Artery Bypass Graft (CABG) surgery (alone or combined with valvular or carotid surgery) within past 12 months - Meets DSM-IV criteria for major or minor depressive episode Exclusion Criteria: - Severe cognitive impairment - Severe psychiatric comorbidity (e.g., alcoholism or schizophrenia) - Severely debilitating or life-threatening illness other than coronary disease
Total Enrollment: 165
Location and Contact Information:
Overall Study Official:
KennethFreedland, Principal Investigator, Washington University School of Medicine
Washington University School of Medicine *Recruiting*
St. Louis, Missouri, 63108
United States
Recruiting Kenneth Freedland
Additional Information:
Study ID Numbers: 60735-01A2;
Study Start Date: January 2002
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00042198
Other Depressive Disorder Studies:
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2. Genetics of the Metabolic Syndrome in Japanese Americans
3. Genetic Epidemiology of Blood Lipids and Obesity - Ancillary to NGHS
4. Black Pooling Project
5. Coronary Disease Morbidity and Mortality in a Population
Related Studies:
Other Depressive Disorder Clinical Trials
Other Missouri Clinical Trials
Other St. Louis Clinical Trials
Treatment of Depression After Coronary Bypass Surgery
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