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This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. Clinical Trials Resources presented on Clinical Trials Search isn't meant to be a substitute for qualified health advice, visits or professional assistance with a real medical. We aren't doctors. Always consult your mD about This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. Clinical research trials and This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. health trials occur in a lot of of places throughout the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new does drugs. The role of the studies / projects is to resolve certain human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector corporations to detect remedies for all varieties of circumstances, such as This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer.. This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. Clinical Trials and other clinical trials allow volunteers to obtain health treatment choices before they are available to the general public. Most times the human subjects recieve professional assistance for free of charge, and every now and again they are paid for their time. Sometimes there is a cost for a This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. clinical trial. Human subjects frequently get the finest healthcare available for their This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer. condition. Risks are a reality, however, and may include extra or frequent physician visits, medical dangers (possibly life-threatening), and/or the treatment being uneffective. Trials are federally governed with strict guidelines to protect clinical trials patients.
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Home > "T" Clinical Trials Conditions > This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer.  This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer.
This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer.
For Condition: Metastases, Neoplasm,Carcinoma, Non-Small-Cell Lung
Status: Recruiting
Sponsor(s): AstraZeneca ,
Synopsis: The purpose of this study is to assess the efficacy and safety of ZD6474 in patients with NSCLC after Failure of Prior Platinum-based Chemotherapy.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Histologic or cytologic confirmation of NSCLC (locally advanced or metastatic, IB-IV) - Failure of first-line platinum-based chemotherapy - WHO Performance status 0 or 1 Exclusion Criteria: - Mixed small cell or non–small-cell histology - Bronchoalveolar carcinoma - Prior chemotherapy or herbal preparations must be discontinued more than 4 weeks before the start of study therapy (6 weeks for nitrosoureas, mitomycin and suramin) - Prior treatment with docetaxel - Prior treatment with agents that block the EGF or VEGF pathways - Significant cardiac event (including symptomatic heart failure or angina) within 3 months of entry or presence of cardiac disease that in the opinion of the Investigator increases the risk of ventricular arrhythmia - History of clinically significant arrhythmia which is symptomatic or requires treatment, or a symptomatic sustained ventricular tachycardia
Total Enrollment: 129
Location and Contact Information:
Research Site *Recruiting*
Billings, Montana,
United States
Recruiting
Research Site *Recruiting*
Atlanta, Georgia,
United States
Recruiting
Research Site *Recruiting*
Jacksonville, Florida,
United States
Recruiting
Research Site *Recruiting*
New York City, New York,
United States
Recruiting
Research Site *Recruiting*
Pittsfield, Massachusetts,
United States
Recruiting
Research Site *Recruiting*
Coos Bay, Oregon,
United States
Recruiting
Research Site *Recruiting*
Great Neck, New York,
United States
Recruiting
Research Site *Recruiting*
New Albany, Indiana,
United States
Recruiting
Additional Information:
Study ID Numbers: 6474IL/0006;
Study Start Date:
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00047840
Other Carcinoma, Non-Small-Cell Lung Studies:
1. A Phase IIa. Open-label, Multicenter, Dose-escalation Study to Assess the Tolerability and Pharmacokinetics of ZD4054 Given Orally Once Daily in Subjects with Metastatic Prostate Cancer
2. Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent with Metastatic Lung Cancer
3. A Trial of ABI-007 in Patients with Advanced Non-Hematologic Malignancies
4. A Phase II Clinical Trial of ABI-007, Administered Weekly in Taxol Resistant Patients with Metastatic Breast Cancer
5. A Phase 2 Trial of ALIMTA (pemetrexed) in Locally Advanced or Metastatic Recurrent Transitional Cell Carcinoma of the Urothelium
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This study is to assess the efficacy and safety of ZD6474 in subjects with Non-small cell lung cancer.
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