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Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or professional assistance by using a genuine doctor. We aren't mDs. Always consult your physician about Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia Clinical research trials and Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia health trials occur in a lot of of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the potency of new does drugs. The role of the studies / undertakings is to figure out specific human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia. Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia Clinical Trials and other clinical trials permit volunteers to get medical treatment choices before they are available to the general public. Many times the test subjects get professional assistance for free of charge, and occasionally they are compensated for their time. Sometimes there is a cost for a Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia clinical trial. Human subjects often get the best healthcare possible for their Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, medical hazards (perhaps life-threatening), and/or the treatment being ineffectual. Trials are federally governed with exacting guidelines to protect clinical trials patients.
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Home > "S" Clinical Trials Conditions > Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia  Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia
Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia
For Condition: Lactic Acidosis,Mitochondrial Myopathy,MELAS Syndrome
Status: Recruiting
Sponsor(s): National Center for Research Resources (NCRR) , University of California, San Diego
Synopsis: OBJECTIVES: I. Study the metabolism of pyruvate and related problems in patients with lactic acidemia. II. Define the nature of the metabolic defect.
Details: PROTOCOL OUTLINE: Patients fast for 6 hours. Glucagon IM is administered after the 6 hour fast. Glucose level is measured at 0, 15, 30, 45, 60, and 90 minutes. In children of sufficient size, alanine and lactic acid should also be measured at each or most of these time points. Fasting continues for at least 18 hours. Glucagon IM is administered again at end of fast. Glucose level is measured at time 0, 15, 30, 45, 60, and 90 minutes.
Eligibility:
Study Type: Observational, Screening
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: - Diagnostically documented elevation in lactate, pyruvate, and/or alanine levels in lactic acidemia patients
Total Enrollment: 35
Location and Contact Information:
Overall Study Official:
RichardHaas, Study Chair, University of California, San Diego
University of California San Diego Medical Center *Recruiting*
San Diego, California, 92103-8757
United States
Recruiting Richard Haas 619-587-4004
Additional Information:
Study ID Numbers: NCRR-M01RR00827-0071; UCSD-071
Study Start Date: December 1978
Record last reviewed: April 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00004353
Other Lactic Acidosis Studies:
1. Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia
2. Dichloroacetate Kinetics, Metabolism and Toxicology
3. Phase III Randomized Study of Sodium Dichloroacetate in Children with Congenital Lactic Acidosis
4. Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia
Related Studies:
Other Lactic Acidosis Clinical Trials
Other California Clinical Trials
Other San Diego Clinical Trials
Study of the Metabolism of Pyruvate and Related Problems in Patients with Lactic Acidemia
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