Search Clinical Trials
 
By Condition
 
By Location (USA)
 
By Location (Other)
 
By Sponsor
 
Resources
 
Privacy Policy
 
About Us
Disclaimer
Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or professional assistance by using a genuine doctor. We aren't mDs. Always consult your physician about Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) Clinical research trials and Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) health trials occur in a lot of of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the potency of new does drugs. The role of the studies / undertakings is to figure out specific human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART). Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) Clinical Trials and other clinical trials permit volunteers to get medical treatment choices before they are available to the general public. Many times the test subjects get professional assistance for free of charge, and occasionally they are compensated for their time. Sometimes there is a cost for a Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) clinical trial. Human subjects often get the best healthcare possible for their Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART) condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, medical hazards (perhaps life-threatening), and/or the treatment being ineffectual. Trials are federally governed with exacting guidelines to protect clinical trials patients.

Home > "S" Clinical Trials Conditions > Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART)

Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART)



Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART)

For Condition: Carcinoma, Non-Small-Cell Lung,Brain Neoplasms,Metastases, Neoplasm
Status: Recruiting
Sponsor(s): Pharmacyclics ,
Synopsis: The primary purpose of the study is to determine if patients with brain metastases from non-small cell lung cancer treated with Motexafin Gadolinium and whole brain radiation therapy retain their neurologic function and ability to think for a longer time compared to patients treated with whole brain radiation therapy alone.
Details:
Eligibility:
Study Type:  Interventional, Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Adults (18 years old) with radiologically proven parenchymal brain metastases from histologically confirmed non-small cell lung cancer; - KPS score of 70; - Each patient must sign a study-specific Informed Consent form Exclusion Criteria: - Liver metastases; - Extracranial metastases in two or more organs; - Known leptomeningeal metastases or subarachnoid spread of tumor; - Prior whole brain radiation; - Plan to use radiosurgery or radiation boost after completion of WBRT; - Planned chemotherapy during study treatment (prior and subsequent chemotherapy is allowed); - Prior total resection of a single brain metastasis; - Laboratory values as follows: LDH > 1.3 x upper limit of normal (ULN); ANC < 1500 /mm³; Platelets < 50,000 /mm³; Creatinine > 2.0 mg/dL; AST or ALT > 2 x ULN; Total bilirubin > 2 x ULN; - Women who are pregnant or lactating
Total Enrollment: 550

Location and Contact Information:


Additional Information:
Study ID Numbers:  PCYC-0211; 
Study Start Date: 
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00054795

Other Brain Neoplasms Studies:
1. Mistletoe Extract and Gemcitabine for the Treatment of Solid Tumor Cancers

2. Study of the Efficacy of an Investigational Drug in Adult Patients with Non Small-Cell Lung Cancer (NSCLC)

3. Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

4. CPG 7909 Injection in non-small cell lung cancer

5. Study of an oral tyrosine kinase inhibitor of VEGFR-2 for the treatment of advanced stage non-small cell lung cancer

Related Studies:

Other Brain Neoplasms Clinical Trials
Other Clinical Trials
Other Munchen Clinical Trials

Study of Neurologic Progression with Motexafin Gadolinium and Radiation Therapy (SMART)
Modify your Search

  Other Brain Neoplasms Clinical Trials
  Other Clinical Trials
  Other Munchen Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103