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Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) Clinical Trials Data presented on Clinical Trials Search is not meant to be a substitute for qualified medical advice, visits or professional assistance with a genuine dr.. We are not doctors. Always consult your mD about Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) Clinical research trials and Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) medical trials take place in many of places throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the effectiveness of new does drugs. The purpose of the studies / projects is to solve specific human healthcare questions. Clinical trials are a popular way for mDs, government agencies, and private sector companies to find cures for all varieties of conditions, like Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML). Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) Clinical Trials and other clinical trials allow for volunteers to have health treatment options before they are available to the masses. Many times the human subjects acquire professional assistance for free of charge, and sometimes they are compensated for their time. Occasionally there is a cost for a Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) clinical trial. Test subjects typically obtain the finest healthcare available for their Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML) condition. Dangers are a reality, nevertheless, and might include additional or frequent doctor trips, medical dangers (possibly life-jeopardising), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials patients.
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Home > "S" Clinical Trials Conditions > Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML)  Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML)
Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML)
For Condition: Acute Myeloid Leukemia
Status: Recruiting
Sponsor(s): Cephalon ,
Synopsis: The purpose of the study is to determine whether CEP-701 given in sequence with induction chemotherapy increases the proportion of patients with relapsed acute myeloid leukemia (AML) who achieve a second complete remission (CR).
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion criteria: - cytological confirmation of AML; - relapsed disease following first CR of 1 month to 24 months duration; - confirmation of FLT-3 activating mutation positive status after point of initial relapse; - aged 18 years or older; - life expectancy greater than 3 mos.; - ECOG Performance Status of 0, 1, 2 Exclusion criteria: - bilirubin > 2x ULN; - ALT/AST > 3x ULN; - serum creatinine > 1.5 mg/dL; - untreated or progressive infection; - known CNS involvement with AML; - any prior treatment with FLT-3 inhibitor; - active GI ulceration or bleeding; - patient requires treatment for HIV with protease inhibitors; - use of investigational drug within 30 days of baseline visit
Total Enrollment: 120
Location and Contact Information:
MD Anderson Cancer Center *Recruiting*
Houston, Texas, 77030
United States
Recruiting Miloslav Beran 713-792-2248
Indiana Cancer Pavillion *Recruiting*
Indianapolis, Indiana, 46202
United States
Recruiting Cheryl Rutledge 317-274-0901
The Mayo Clinic *Recruiting*
Rochester, Minnesota, 55905
United States
Recruiting Colleen Irlbeck 507-538-0107
University of Nebraska *Recruiting*
Omaha, Nebraska, 68198
United States
Recruiting Patricia Pedersen 402-559-4810
Johns Hopkins *Recruiting*
Baltimore, Maryland, 21231
United States
Recruiting Doug Smith 410-614-5068
University of Michigan *Recruiting*
Ann Arbor, Michigan, 48109
United States
Recruiting Irene Ryan 734-647-9757
Additional Information:
Study ID Numbers: C701a/204/ON/US;
Study Start Date: October 2003
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00079482
Other Acute Myeloid Leukemia Studies:
1. Acute Myeloid Leukemia Study
2. flt3L in Treating Patients With Acute Myeloid Leukemia
3. Fluconazole Compared With Voriconazole in Preventing Invasive Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Transplantation
4. Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia
5. Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
Related Studies:
Other Acute Myeloid Leukemia Clinical Trials
Other Nebraska Clinical Trials
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Study of CEP-701 in Patients with Acute Myeloid Leukemia (AML)
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