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Home > "S" Clinical Trials Conditions > Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer



Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

For Condition: Carcinoma, Non-Small-Cell Lung
Status: No longer recruiting
Sponsor(s): Bristol-Myers Squibb ,
Synopsis: Taxol and carboplatin are commonly used drugs for the treatment of stage IIIB or IV non small cell lung carcinoma. This study compares treatment with Taxol/carboplatin given every 3 weeks to a schedule where it is given weekly. The purpose of the study is to determine the most effective and safe schedule for giving these drugs in non small cell lung carcinoma.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Open Label, Active Control, Crossover Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion criteria: - Confirmation of non-small cell bronchogenic carcinoma (epidermoid, squamous, adeno, large cell anaplastic carcinoma, but no small cell or carcinoid) must be histologically or cytologically confirmed. - No prior antineoplastic chemotherapy, hormonal therapy or therapy with biological response modifiers - No previous irradiation to the only area of measurable disease. Exclusion Criteria: - Past or current history of neoplasm other than the entry diagnosis. Exceptions are curatively treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix or other cancers treated by surgery or radiation with a disease free survival longer than 5 years. - Patients who have undergone surgery less than 3 weeks prior to enrollment. - History of serious cardiac disease not adequately controlled. - Patients with serious active infections or other serious underlying medical condition. - Uncontrolled diabetes mellitis.
Total Enrollment: 444

Location and Contact Information:

West Suburban Center for Cancer Care
River Forest,  Illinois,  60305
United States
 

Mid Illinois Hematology and Oncology Associates, Ltd.
Normal,  Illinois,  61761
United States
 

Fairview-University Medical Center, University of Minnesota
Minneapolis,  Minnesota,  55455
United States
 

Wellstar Cobb Hospital
Austell,  Georgia,  30060
United States
 

Mercy Cancer Center
Mason City,  Iowa,  50401
United States
 

Good Samaritan Medical Center
West Palm Beach,  Florida,  33401
United States
 

Don & Sybil Harrington Cancer Center
Amarillo,  Texas,  79106
United States
 

Little Rock Hematology/Oncology Associates
Little Rock,  Arkansas,  72205
United States
 

Mid Dakota Clinic
Bismark,  North Dakota,  58501
United States
 

Danbury Hospital/Praxair Cancer Center
Danbury,  Connecticut,  06810
United States
 

Madigan Army Medical Center
Tacoma,  Washington,  98431
United States
 

Metro Minnesota CCOP
St. Louis Park,  Minnesota,  55416
United States
 

Associated Physicians & Surgeons Clinic, LLC
Terre Haute,  Indiana,  47804
United States
 

Siouxland Hematology/Oncology Associates
Sioux City,  Iowa,  51101
United States
 

Southwest Regional Cancer Center
Austin,  Texas,  78705
United States
 

Hematology-Oncology of Central New Jersey
Red Bank,  New Jersey,  07701
United States
 

Central Pennsylvania Hematology & Medical Oncology Associates, P.C.
Lemoyne,  Pennsylvania,  17043
United States
 

Northwest Medical Specialties, PLLC
Tacoma,  Washington,  98405
United States
 

Quadrangle Medical Specialists, Southern Oncology Research
Greenville,  North Carolina,  27834
United States
 

Raleigh Hematology Associates, Wake Practice
Cary,  North Carolina,  27609
United States
 

Naval Medical Center
San Diego,  California,  92134
United States
 

Jewish Medical Plaza
Louisville,  Kentucky,  40202
United States
 

The Center for Cancer and Hematologic Disease
Cherry Hill,  New Jersey,  08003
United States
 

Brackenridge Hospital
Austin,  Texas,  78701
United States
 

New Mexico Oncology Hematology Consultants
Albuquerque,  New Mexico,  87109
United States
 

Maimonides Medical Center
Brooklyn,  New York,  11209
United States
 

Boston Cancer Group, PLC
Memphis,  Tennessee,  38104
United States
 

Clifton Springs Hospital and Clinic
Clifton Springs,  New York,  14432
United States
 

Advanced Oncology Associates
Armonk,  New York,  10504
United States
 

Ellis Fischel Cancer Center
Columbia,  Missouri,  65203
United States
 

Upstate New York Cancer R & E
Rochester,  New York,  14623
United States
 

Community Medical Center
Toms River,  New Jersey,  08755
United States
 

Joliet Oncology/Hematology Associates,Ltd.
Joliet,  Illinois,  60435
United States
 

Beth Israel Deaconess Medical Center
Boston,  Massachusetts,  02215
United States
 

Columbus CCOP
Columbus,  Ohio,  43206
United States
 

Hematology and Oncology Associates of Southern Michigan,P.C
Jackson,  Michigan,  49201
United States
 

Washington VA Medical Center
Washington D.C.,  District of Columbia,  20422
United States
 

Community Cancer Care, Inc.
Indianapolis,  Indiana,  46202
United States
 

Hematology/Oncology of Rockland
New York City,  New York, 
United States
 

Albert Einstein Healthcare Network
Philadelphia,  Pennsylvania,  19141
United States
 

Genesis Cancer Center
Hot Springs,  Arkansas,  71913
United States
 

University of Louisville
Louisville,  Kentucky,  40202
United States
 

Walter Reed Army Hospital
Washington D.C.,  District of Columbia,  20307
United States
 

Hennepin County Medical Center
Minneapolis,  Minnesota,  55415
United States
 

Louisiana State University Health Sciences Center
Shreveport,  Louisiana,  71130
United States
 

University of Pittsburgh Medical Center/University of Pittsburgh Cancer Institute
Pittsburgh,  Pennsylvania,  15213
United States
 

Goshen Medical Associates
Goshen,  New York,  10924
United States
 

New York Oncology-Hematology,P.C./Capital District Hematology, Oncology Associates
Latham,  New York,  12110
United States
 

Southwest Cancer Center
Lubbock,  Texas,  79415
United States
 

Guthrie Clinic Ltd
Sayre,  Pennsylvania,  18840
United States
 

Brooklyn VA
Brooklyn,  New York,  11209
United States
 

Maine General Medical Center
Waterville,  Maine,  04901
United States
 

Medical Oncology Care Associates
Orange,  California,  92868
United States
 

Highlands Oncology Group
Springdale,  Arkansas,  72764
United States
 

Creighton University Cancer Center
Omaha,  Nebraska,  68131
United States
 

Louisiana Oncology Associates
Lafayette,  Louisiana,  70506
United States
 


Additional Information:
Study ID Numbers:
  BMS TAX/MEN.12; 
Study Start Date: June 2000
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00035152

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4. Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients with Stage III/IV and Relapsed NSCLC

5. Pilot Study of the Correlation Between the Findings of Atypical/Malignant Cells in Sputum and Fluorescence Bronchoscopy in Patients at Risk for Lung Cancer of the LIFE Imaging System and White Light Bronchoscopy

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