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Short Course Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) (750 mg)



Short Course Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) (750 mg)

For Condition: Bronchitis, Chronic
Status: Completed
Sponsor(s): Johnson & Johnson Pharmaceutical Research and Development, L.L.C. , Ortho-McNeil Pharmaceutical
Synopsis: The purpose of this study is to see if just 3 to 5 days of LEVAQUIN® 750 mg is as good as 5 days of ZITHROMAX® 250 mg or 10 days of AUGMENTIN® 875 mg in the treatment of acute bacterial exacerbation of chronic bronchitis (ABECB), and to see if there is a difference in side effects between the three drugs.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria (including but not limited to): - History of chronic bronchitis - Diagnosis of Type-1 or Type-2 acute bacterial exacerbation of chronic bronchitis (ABECB) - If female patient: must be postmenopausal for at least 1 year, OR have hysterectomy, OR bilateral tubal ligation or otherwise incapable of pregnancy. Exclusion Criteria (including but not limited to): - Diagnosis of bronchial asthma - Allergy or serious adverse reaction to any of the study medications or other quinolone or other penicillin or other macrolide - Failed treatment of pneumonia or ABECB in past three months with any of the study medications or other quinolone or other penicillin or other macrolide - Can not tolerate medication taken by mouth.
Total Enrollment: 

Location and Contact Information:


Additional Information:
Study ID Numbers:
  CAPSS-197; 
Study Start Date: 
Record last reviewed: February 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00042718

Other Bronchitis, Chronic Studies:
1. A blinded study comparing the safety and efficacy of a fully human anti-IL8 monoclonal antibody (ABX-IL8) to placebo in patients with chronic bronchitis and COPD

2. Short Course Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB) (750 mg)

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