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Segmental Bronchoalveolar Lavage Clinical Trials Information presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, trips or professional assistance with a real medical doctor. We aren't docs. Always confer with your doctor about Segmental Bronchoalveolar Lavage conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Segmental Bronchoalveolar Lavage Clinical research trials and Segmental Bronchoalveolar Lavage health trials happen in many of cities across the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the effectualness of new does drugs. The intention of the studies / projects is to figure out particular human healthcare questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to detect cures for all forms of circumstances, like Segmental Bronchoalveolar Lavage. Segmental Bronchoalveolar Lavage Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment options before they are available to the general public. Most times the subjects get treatment for free of charge, and occasionally they are paid for their time. Occasionally there is a cost for a Segmental Bronchoalveolar Lavage clinical trial. Subjects frequently get the best healthcare possible for their Segmental Bronchoalveolar Lavage condition. Hazards are a reality, however, and could include more or frequent mD visits, health risks (possibly life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with exacting guidelines to protect clinical trials patients.
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Home > "S" Clinical Trials Conditions > Segmental Bronchoalveolar Lavage  Segmental Bronchoalveolar Lavage
Segmental Bronchoalveolar Lavage
For Condition: Asthma,Chronic Obstructive Airway Disease,Healthy,Lung Disease,Pulmonary Fibrosis
Status: Recruiting
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: Bronchoalveolar lavage is a diagnostic and therapeutic procedure conducted by placing a fiberoptic scope into the lung of a patient, and injecting sterile water (saline) into the lung and removing. The sterile water removed contains secretions, cells, and protein from the lower respiratory tract. This sample can be analyzed to provide more information about possible disease processes going on in the lungs. This protocol will be used to perform BAL, bronchial brushing, and bronchial wall biopsy in normal volunteers. The samples collected during the study will be used to examine biochemical processes in the lung that may contribute to lung disease
Details: This protocol proposes to perform bronchoalveolar lavage, bronchial brushing and bronchial wall biopsy in research volunteers and in patients with pulmonary disease to evaluate the cellular components of normal and diseased lungs. This research study will help to improve our understanding of pathogenic mechanisms in the lung during progression of pulmonary disease.
Eligibility:
Study Type: Observational, Screening
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA Patients and research volunteers will be accepted for bronchoscopy and bronchoalveolar lavage only if their heath status will not be compromised by the procedure. EXCLUSION CRITERIA Patients or research volunteers with abnormalities that contraindicate, or increase the risk of, fiberoptic bronchoscopy and bronchoalveolar lavage, including a history of allergy to atropine, lidocaine, or other topical anesthetics or premedications; FEV(1) less than 0.8 liters; PaO(2), on supplemental 02, of less than 70 mmHg or PaCO(2) greater than 45 mmHg; presence of uncorrected clotting disorder, uncontrolled hypertension, significant cardiac disease, renal or liver failure; metastatic disease; hematologic disorders such as severe anemia (hemoglobin less than or equal to 7 g/ml), granulocytopenia, or platelet disorders. Patients or research volunteers with a positive serum test for human immunodeficiency virus or hepatitis B or C. Patients or research volunteers who are pregnant or lactating. Patients or research volunteers who are incapable of giving informed consent .
Total Enrollment: 9999
Location and Contact Information:
National Heart, Lung and Blood Institute (NHLBI) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Patient and Public Liaison Office 1-800-411-1222
Additional Information:
Study ID Numbers: 970022; 97-H-0022
Study Start Date: November 15, 1996
Record last reviewed: October 10, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001618
Other Asthma Studies:
1. Benefits and Risks of Newborn Screening for Cystic Fibrosis
2. Evaluation and Treatment of Patients with Lung Disease not Participating in Research
3. An Open-Label Study of the Safety of Interferon gamma-1b in Patients with IPF
4. Natrecor in Pulmonary Hypertension
5. Ozone Exposure and Dose Delivered to Human Lungs
Related Studies:
Other Asthma Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Segmental Bronchoalveolar Lavage
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