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Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. Clinical Trials Data presented on Clinical Trials Search is not meant to be a substitute for qualified medical advice, visits or professional assistance with a genuine dr.. We are not doctors. Always consult your mD about Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. Clinical research trials and Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. medical trials take place in many of places throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the effectiveness of new does drugs. The purpose of the studies / projects is to solve specific human healthcare questions. Clinical trials are a popular way for mDs, government agencies, and private sector companies to find cures for all varieties of conditions, like Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.. Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. Clinical Trials and other clinical trials allow for volunteers to have health treatment options before they are available to the masses. Many times the human subjects acquire professional assistance for free of charge, and sometimes they are compensated for their time. Occasionally there is a cost for a Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. clinical trial. Test subjects typically obtain the finest healthcare available for their Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. condition. Dangers are a reality, nevertheless, and might include additional or frequent doctor trips, medical dangers (possibly life-jeopardising), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials patients.
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Home > "R" Clinical Trials Conditions > Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
For Condition: Candidiasis, esophageal,HIV Infections
Status: Completed
Sponsor(s): Janssen Pharmaceutica ,
Synopsis: To evaluate the safety and efficacy of itraconazole oral solution versus fluconazole tablets for the treatment of esophageal candidiasis in immunocompromised patients.
Details:
Eligibility:
Study Type: Interventional, Treatment, Double-Blind, Safety Study
Minimum Age/Maximum Age: 13 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - Esophageal candidiasis. - Histological evidence of Candida spp. at baseline with confirmation by positive mycological culture. - HIV infection or other predisposing risk factor. - Life expectancy of at least 2 months. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: - Malignancies of the head or neck, if the treatment or disease will interfere with response assessment. - Evidence of systemic fungal infection. - Underlying clinical condition that would preclude study completion. - Judged to be unreliable in regard to following physician's directives. Concurrent Medication: Excluded: - Rifampin. - Rifabutin. - Phenobarbital. - Phenytoin. - Carbamazepine. - Terfenadine. - Astemizole. - H2 blockers. - Continual antacids. - Any investigational drug (expanded access drugs are allowed). Patients with the following prior conditions are excluded: - History of significant hepatic abnormalities or clinical evidence of hepatic disease within 2 months prior to study entry. - History of hypersensitivity to imidazole or azole compounds. Prior Medication: Excluded: - Other orally administered antifungal therapy within 3 days prior to study entry. - Any investigational drug within 1 month prior to study entry (expanded access drugs are allowed).
Total Enrollment:
Location and Contact Information:
Univ Hosps of Cleveland
Cleveland, Ohio, 44106
United States
Dr Eskild A Petersen
Tucson, Arizona, 85724
United States
George Washington Univ Med Ctr
Washington D.C., District of Columbia, 20037
United States
Emory Univ School of Medicine
Atlanta, Georgia, 30303
United States
Austin Infectious Disease Consultants
Austin, Texas, 78705
United States
Univ of North Carolina
Chapel Hill, North Carolina, 27599
United States
Johns Hopkins Univ School of Medicine
Baltimore, Maryland, 21205
United States
Wayne State Univ / Harper Hosp
Detroit, Michigan, 48201
United States
Erie County Med Ctr
Buffalo, New York, 14215
United States
Rush Presbyterian - Saint Luke's Med Ctr
Chicago, Illinois, 60612
United States
UCSD Med Ctr
San Diego, California, 92103
United States
Montefiore Med Ctr
Bronx, New York, 10467
United States
Houston Veterans Administration Med Ctr
Houston, Texas, 77030
United States
Dr Douglas Dieterich
New York City, New York, 10016
United States
Infectious Diseases Association / Research Med Ctr
Kansas City, Missouri, 64132
United States
Bowman Gray School of Medicine
Winston Salem, North Carolina, 27157
United States
Los Angeles County - USC Med Ctr
Los Angeles, California, 90033
United States
Univ of Missouri at Kansas City School of Medicine
Kansas City, Missouri, 64108
United States
Additional Information:
Study ID Numbers: 236A; ITR-USA-12
Study Start Date:
Record last reviewed: April 1996
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002132
Other Hiv Infections Studies:
1. A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs
2. Gene Therapy in HIV-Positive Patients with Non-Hodgkin's Lymphoma
3. Evaluation and Natural History of Children with Cancer and AIDS
4. Reducing the Transmission of HIV in China
5. The Safety and Effectiveness of Zidovudine Plus Acyclovir in Patients with Early HIV Infection
Related Studies:
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Other District of Columbia Clinical Trials
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Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
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