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Home > "P" Clinical Trials Conditions > Prevention of Depression in At-Risk Adolescents  Prevention of Depression in At-Risk Adolescents
Prevention of Depression in At-Risk Adolescents
For Condition: Depression
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to determine the impact of a group cognitive behavioral program (CBP) on the depressive symptoms and disorders of adolescents at risk for developing depression.
Details: Depression is a prevalent, chronic, and impairing condition that is often undetected and becomes more difficult to treat as chronicity increases. There is an increasing need to develop large-scale depression prevention studies in adolescents. This study will evaluate a cognitive-behavioral prevention program to determine its effectiveness in preventing depression in at-risk adolescents. The study also will ascertain the costs and benefits of incorporating this intervention into "real world" settings. Participants in this study will be randomly assigned to receive either CBP or usual care for 32 months. Depressive symptoms, levels of functioning, and medical and mental health care utilization will be assessed at baseline and again at 2, 8, 20, and 32 months after intake.
Eligibility:
Study Type: Interventional, Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 13 Years/17 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Have a parent with depression - Past depressive episode or current subsyndromal depressive symptoms
Total Enrollment: 320
Location and Contact Information:
University of Pittsburgh School of Medicine *Recruiting*
Pittsburgh, Pennsylvania, 15213-2593
United States
Recruiting David Brent 412-624-5172
Kaiser Permanente Center for Health Research *Recruiting*
Portland, Oregon, 97227
United States
Recruiting Greg Clarke 503-335-6673
Vanderbilt University *Recruiting*
Nashville, Tennessee, 37203-5721
United States
Recruiting Judy Garber 615-343-8714
Harvard University Medical School *Recruiting*
Boston, Massachusetts, 02115-5794
United States
Recruiting William Beardslee 617-232-8390
Additional Information:
Study ID Numbers: MH64735-01A1-2;
Study Start Date: August 2003
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00073671
Other Depression Studies:
1. Drug Therapy to Treat Minor Depression
2. Multiphase Efficacy Study of venlafaxine ER to Treat Recurrent Depression
3. Prevention of Depression in At-Risk Adolescents
4. Combination Chemotherapy Plus Fluoxetine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
5. Magnetic Stimulation for Parkinson Disease
Related Studies:
Other Depression Clinical Trials
Other Pennsylvania Clinical Trials
Other Pittsburgh Clinical Trials
Prevention of Depression in At-Risk Adolescents
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