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Preventing Post-Stroke Depression Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Preventing Post-Stroke Depression conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Preventing Post-Stroke Depression Clinical research trials and Preventing Post-Stroke Depression health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Preventing Post-Stroke Depression. Preventing Post-Stroke Depression Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Preventing Post-Stroke Depression clinical trial. Participants oftentimes recieve the most expert healthcare available for their Preventing Post-Stroke Depression condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "P" Clinical Trials Conditions > Preventing Post-Stroke Depression  Preventing Post-Stroke Depression
Preventing Post-Stroke Depression
For Condition: Depression,Cerebrovascular Accident
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to evaluate the effectiveness of both drug and nondrug treatments in preventing depression after a stroke.
Details: The development of depression after a stroke is a serious condition that can have negative effects on thought, emotions, and overall daily functioning, particularly in the first year following the stroke. Evidence suggests that antidepressants may be used to prevent post-stroke depression. This study will treat nondepressed stroke patients with antidepressants or problem solving therapy (PST) to determine the most effective treatments for preventing depression. Participants in this study will be randomly assigned to receive PST, escitalopram, or placebo (an inactive pill) for 12 months. Participants who display depressive symptoms for 2 weeks or more will be removed from the study. After 12 months, treatment will be discontinued and participants will be monitored for an additional 6 months.
Eligibility:
Study Type: Interventional, Prevention, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 31 Years/89 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Stroke within the last 120 days Exclusion Criteria: - DSM IV criteria for major or minor depressive disorder - Heart, respiratory, kidney, or liver failure; severely disabling musculoskeletal disorder; or cancer - Diagnosis of neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease, Multiple System Atrophy, or Huntington’s disease - Pre-existing dementia or aphasia with severe language comprehension deficits - Alcohol or substance abuse or dependence within the last 12 months - Recurrent unipolar or bipolar disorder prior to the stroke
Total Enrollment: 201
Location and Contact Information:
University of Iowa Hospitals and Clinics *Recruiting*
Iowa City, Iowa, 52242-1000
United States
Recruiting Stephanie Rosazza 319-353-5807
Burke Rehabilitation Hospital *Recruiting*
White Plains, New York, 10605
United States
Recruiting Pasquale Fonzetti 914-597-2502
University of Chicago *Recruiting*
Chicago, Illinois, 60637
United States
Recruiting Ana Solodkin 773-834-7706
Additional Information:
Study ID Numbers: 65134-01A1;
Study Start Date: September 2002
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00071643
Other Depression Studies:
1. Sertraline and Cognitive Therapy in Depressed Alcoholics
2. Effects of Therapist Behavior on the Treatment of Depressed Adolescents
3. Dextroamphetamine-Amphetamine Compared With Methylphenidate in Treating Children With Depression and Problems With Memory, Attention, and Thinking Caused By Cancer Treatment
4. Prevention of School Dropout for Mexican American Adolescents
5. Genetics of Fibromyalgia
Related Studies:
Other Depression Clinical Trials
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Other Iowa City Clinical Trials
Preventing Post-Stroke Depression
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