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Home > "P" Clinical Trials Conditions > Physical Fitness and Cardiovascular Mortality in Firefighters  Physical Fitness and Cardiovascular Mortality in Firefighters
Physical Fitness and Cardiovascular Mortality in Firefighters
For Condition: Coronary Disease,Heart Diseases,Hypertension,Obesity,Cardiovascular Diseases
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: To study prospectively the interrelationships among physical fitness, activity, other measured risk factors, coronary heart disease (CHD) and all-cause mortality in a cohort of 3,403 firefighters.
Details: BACKGROUND: From 1971-1991 the Occupational Health Service of Los Angeles Country measured physical fitness and other CHD risk factors (including physical activity, anthropometric measures, blood pressure, smoking, family history of CHD, and levels of total cholesterol, uric acid, and glucose) in Los Angeles County firefighters at application and routine intervals (approximately every three years). The entire cohort of 3403 firefighters is now followed for mortality up to 1996. DESIGN NARRATIVE: The entire cohort of 3,403 firefighers is followed up to 1996 in this longitudinal study. The investigators are using a variety of tracing sources, including the National Death Index, and obtaining death certificates to determine date and cause of death. Cohort data will be analyzed to address the following aims: (1) To provide a longitudinal description of and determine the interrelationships among physical fitness, physical activity, and other measured risk factors; (2) to determine whether levels of physical fitness are related, independently of other known and measured risk factors, CHD and all-cause mortality; (3) To determine whether there is a gradient of decreasing CHD risk with increasing levels of physical fitness, or whether there appears to be some threshold of physical fitness, above which CHD risk stabilizes; (4) To determine whether the relationship between physical fitness and CHD and all-cause mortality varies by such cardiovascular risk factors as age, cholesterol levels, blood pressure, smoking, and obesity.
Eligibility:
Study Type: Observational, Natural History, Longitudinal, Defined Population
Minimum Age/Maximum Age: /
Genders: Male
Protocol Entry Criteria: No eligibility criteria
Total Enrollment:
Location and Contact Information:
Overall Study Official:
WendyMack, , University of Southern California
Additional Information:
Study ID Numbers: 5080;
Study Start Date: July 1999
Record last reviewed: November 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005540
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