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PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or professional assistance by using a genuine doctor. We aren't mDs. Always consult your physician about PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin Clinical research trials and PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin health trials occur in a lot of of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the potency of new does drugs. The role of the studies / undertakings is to figure out specific human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all sorts of conditions, including PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin. PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin Clinical Trials and other clinical trials permit volunteers to get medical treatment choices before they are available to the general public. Many times the test subjects get professional assistance for free of charge, and occasionally they are compensated for their time. Sometimes there is a cost for a PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin clinical trial. Human subjects often get the best healthcare possible for their PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, medical hazards (perhaps life-threatening), and/or the treatment being ineffectual. Trials are federally governed with exacting guidelines to protect clinical trials patients.
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Home > "P" Clinical Trials Conditions > PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin  PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin
PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin
For Condition: Cirrhosis,Chronic Hepatitis C,Liver Fibrosis
Status: Recruiting
Sponsor(s): Schering-Plough ,
Synopsis: The objective of this study is to determine the effectiveness of PEG-Intron 1.5 ug/kg/wk plus REBETOL 800-1400 mg/day in adults with chronic hepatitis C with moderate to severe liver fibrosis or cirrhosis who failed to respond to previous treatment with an a interferon in combination with ribavirin. Patients who do not respond to PEG-Intron plus Rebetol will be enrolled in a long-term maintenance study to evaluate the effectiveness of PEG-intron therapy monotherapy versus no treatment for the prevention of disease progression (Protocols P02569 and P02570).
Details:
Eligibility:
Study Type: Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Age at entry 18-65 - Positive for Hepatitis C - Nonresponder to previous treatment (minimum of 3 months) with an a-Interferon plus ribavirin - Liver Biopsy demonstrating moderate to severe fibrosis or cirrhosis Exclusion Criteria: - Any cause for the liver disease other than chronic hepatitis C - History or presence of complications of cirrhosis - Alcohol or illicit drug use or methadone treatment within the past 2 years - Treatment for chronic hepatitis C within the previous 6 months - Diseases or conditions that could interfere with the subject's participation in and completion of the study
Total Enrollment: 2200
Location and Contact Information:
Johns Hopkins University *Recruiting*
Baltimore, Maryland, 21287
United States
Recruiting Mark Sulkowski 410-614-4172
William Beaumont Hospital *Recruiting*
Royal Oak, Michigan, 48073
United States
Recruiting Stuart Gordon 248-551-5134
Queen Elizabeth II Health Sciences Center *Recruiting*
Halifax, ,
Canada
Recruiting Kevork Peltakian
Servico de Medicina III - Huc *Recruiting*
Coimbra, ,
Portugal
Recruiting Armando Carvalho 351239400400
Hippokration General Hospital of Athens *Recruiting*
ATHENS, ,
Greece
Recruiting Emmanuel Manesis 30 210 7778742
VA Medical Center *Recruiting*
San Juan, ,
Puerto Rico
Recruiting Doris Toro
Elisabethinen Hospital Linz *Recruiting*
Linz, ,
Austria
Recruiting Franz Hackl 43 732 7676 3140
Burrard Medical Building *Recruiting*
Vancouver, ,
Canada
Recruiting Robert Enns 604-688-7017
University of Miami *Recruiting*
Miami, Florida, 33136
United States
Recruiting Eugene Schiff 305-243-2854
Hospital Universitario Edgard Santos *Not yet recruiting*
Salvador, ,
Brazil
Not yet recruiting Raimundo Parana 5571/ 2474651
Dr. Rodolfo Rossi *Recruiting*
La Plata, ,
Argentina
Recruiting Jose Curciarello 542214828821
University of Missouri Hopsital *Recruiting*
Columbia, Missouri, 65212
United States
Recruiting Paul King 573-882-4894
Duke University Medical School *Recruiting*
Durham, North Carolina, 27710
United States
Recruiting John McHutchison 919-668-7177
MNR-Klinik, Gastroenterologie *Recruiting*
Duesseldorf, ,
Germany
Recruiting Dieter Haeussinger 49-211-811-7569
A.P.H. Paris, Hopital Beaujon *Recruiting*
Clichy, ,
France
Recruiting Patrick Marcellin 01-4087-5095
Lainz Hospital of Vienna *Recruiting*
Vienna, ,
Austria
Recruiting Harald Brunner 43 1 80110 2643
Azienda Ospedaliera Careggi *Recruiting*
Firenze, ,
Italy
Recruiting Anna Zignego +390554296400
Hospital das Clinicas Dafmusp *Recruiting*
Sao Paulo, ,
Brazil
Recruiting Flair Carrilho 5511-30615544
Hospital Amaral Carvalho *Recruiting*
Jau, ,
Brazil
Recruiting Marcos Mauad 5514 620 1270
Ochsner Clinic Foundation *Recruiting*
New Orleans, Louisiana, 70121
United States
Recruiting Robert Perrillo 504-824-7466
Universitaetskliniken des Saarlandes - Innere Med. *Recruiting*
HOMBURG / SAAR, ,
Germany
Recruiting Stefan Zeuzem 49-6841-16-23202
Hopsital Sao Rafael *Recruiting*
Salvador - BA, ,
Brazil
Recruiting Luiz Lyra 5571/393-1021
205 College Plaza *Recruiting*
Edmonton, ,
Canada
Recruiting Klaus Gutfreund
Hospices Civils de Lyon, Hotel Dieu *Recruiting*
Lyon Cedex 2, , 69288
France
Recruiting Christian Trepo 0472413140
Hopital da Arrabida *Recruiting*
V.N. de Gaia, ,
Portugal
Recruiting Ana Vale
Fremantle Hospital *Recruiting*
Fremantle, ,
Australia
Recruiting Lindsay Mollison 618-9431-2912
John Buhler Research Centre *Recruiting*
Winnipeg, ,
Canada
Recruiting Kelly Kaita 204-977-6519
Policlinico S. Orsola-Malpighi *Recruiting*
Bologna, ,
Italy
Recruiting Guiseppe Mazzella +390516363276
Inova Fairfax Hopsital *Recruiting*
Falls Church, Virginia, 22042
United States
Recruiting Zobair Younossi 703-698-3182
Minnesota Clinical Research Center *Recruiting*
St. Paul, Minnesota, 55443
United States
Recruiting Coleman Smith 612-871-1145
Udaondo Hospital Municipal de Gastroenterologie *Recruiting*
Buenos Aires, ,
Argentina
Recruiting Ruben Terg 54-11-4306-7362
Hospital F.J. Muniz *Recruiting*
Buenos Aires, ,
Argentina
Recruiting Hugo Fainboim 54 11 4304 4655
Policlinico Universitario di Modena *Recruiting*
Modena, ,
Italy
Recruiting Erica Villa 39 059 4224 359
Metroplitan Research *Recruiting*
Fairfax, Virginia, 22031
United States
Recruiting Vinod Rustgi 703-698-9254
Royal Free Hospital *Recruiting*
London, ,
United Kingdom
Recruiting Geoffrey Dusheiko 0207 7433 2885
C.H.R. d'Orleans, Hopital de la Source *Recruiting*
Orleans, ,
France
Recruiting Xavier Causse 02 38 51 47 04
C.H.U. de Toulouse, Hopital de Purpan *Recruiting*
Toulouse, , 31059
France
Recruiting Karl Barange 05 61 77 94 42
Hospital das Clinicas da UNICAMP *Recruiting*
Campinas - SP, ,
Brazil
Recruiting Fernando Goncales 5519-3788-8600
Milton S. Hershey Medical Center *Recruiting*
Hershey, Pennsylvania, 17033
United States
Recruiting Thomas McGarrity 717-531-8300
A.P.H. Paris, Hospital Pitie-Salpetriere *Recruiting*
Paris Cedex 13, , 75651
France
Recruiting Thierry Poynard 01-45-86-20-22
St. Francis Medical Center *Recruiting*
Honolulu, Hawaii, 96817
United States
Recruiting Naoky Tsai 808-547-6543
London Health Sciences Center - University Campus *Recruiting*
London, ,
Canada
Recruiting Paul Marotta 519-663-3406
Scripps Clinic *Recruiting*
LaJolla, California, 92037
United States
Recruiting Paul Pockros 858-554-8879
Sir Charles Gairdner Hospital *Recruiting*
Nedlands, ,
Australia
Recruiting Gary Jeffrey 618-9346-3228
University of Pittsburg *Recruiting*
Pittsburgh, Pennsylvania, 15213
United States
Recruiting Obaid Shakil
Fundacion Cardioinfantil *Recruiting*
Bogota, ,
Colombia
Recruiting Victor Idrovo 57-1-610-8280
Hospital Sao Paolo - Universidade Federal Sao Paolo *Recruiting*
Sao Paolo, ,
Brazil
Recruiting Maria Ferraz 5511-55764463
450 E. 69th Street *Recruiting*
New York City, New York, 10021
United States
Recruiting Ira Jacobson 212-746-2115
A.P.H. Paris, Hopital Saint Antoine *Recruiting*
Paris cedex, ,
France
Recruiting Raoul Poupon 01 49 28 23 78
Indiana Univeersity *Recruiting*
Indianapolis, Indiana, 46202
United States
Recruiting Paul Kwo
Salzburg General Hospital *No longer recruiting*
Salzburg, ,
Austria
No longer recruiting
Ponce Gastroenterology Research *Recruiting*
Ponce, ,
Puerto Rico
Recruiting Alvaro Reymunde 787 840-8686
Irmandade da Santa Casa de Misericordia *Recruiting*
Porto Alagre - RS, ,
Brazil
Recruiting Angelo Mattos 5551-3214-8080
University of Iowa *Recruiting*
Iowa City, Iowa, 52242
United States
Recruiting Douglas Labrecque
Carolina Center for Liver Disease *Recruiting*
Charlotte, North Carolina, 28203
United States
Recruiting Robert Reindollar 704-378-4371
MetroHealth Medical Center *Recruiting*
Cleveland, Ohio, 44109
United States
Recruiting Arthur McCullough 216-778-5114
The Toronto General Hospital - University Health Network *Recruiting*
Toronto, ,
Canada
Recruiting Florence Wong 416-340-5019
St. Josef-Hospital Oberhausen *Recruiting*
Oberhausen, ,
Germany
Recruiting Claus Niederau +49 208 837 -301
Universitaetsspital Zuerich *Recruiting*
Zuerich, ,
Switzerland
Recruiting Eberhard Renner 41 1 255 25 53
Hospital Provicial Del Centenario *Recruiting*
Rosario, ,
Argentina
Recruiting Hugo Tanno 54 11 341 439511
Hopital de l'Archet 2 *Recruiting*
Nice Cedex, ,
France
Recruiting Albert Tran 04 92 03 61 68
Universitaetsklinikum Charite - Campus Virchow Klin *Recruiting*
Berlin, ,
Germany
Recruiting Uwe Hopf 0049-30-450-553071
Concord Hospital *Not yet recruiting*
Sydney, ,
Australia
Not yet recruiting Meng Ngu 612-9767-6804
Centro Medico Nacional Siglo XXI I.M.S.S *No longer recruiting*
Mexico, D.F., ,
Mexico
No longer recruiting
Hopsital Universitario Austral *Recruiting*
Pilar, ,
Argentina
Recruiting Marcelo Silva 54-2322-482884
Mount Sinai Hospital *Recruiting*
Toronto, ,
Canada
Recruiting Saya Feinman 416-586-5301
Aker Sykehus *Recruiting*
Oslo, ,
Norway
Recruiting Helge Bell 47 22 89 40 00
University of Louisville *Recruiting*
Louisville, Kentucky, 40202
United States
Recruiting Luis Marsano
Klinikum Grosshadern/LMU/Med. Klinik + Poliklinik II *Not yet recruiting*
Munich, ,
Germany
Not yet recruiting Reinhart Zachoval 49-89-7095-3018
Royal Perth Hospital *Recruiting*
Perth, ,
Australia
Recruiting Wendy Cheng 618-9224-2179
Jewish General Hospital *Recruiting*
Montreal, ,
Canada
Recruiting Nir Hilzenrat 514-340-8286
Hopsital General Universitario de Valencia *Recruiting*
Valencia, ,
Spain
Recruiting Moises Diago
Ospedale San Paolo *Recruiting*
Milano, ,
Italy
Recruiting Mauro Podda +390281844275
CIF Biotec/Hospital Medica Sur *Recruiting*
Mexico, ,
Mexico
Recruiting Jorge-Louis Poo-Ramirez 5255-5447-1369
Policlinico Unversitario di Padova *Recruiting*
Padova, ,
Italy
Recruiting Alfredo Alberti +36-049-82.12.293
Rheinische Friedrich-Wilhelms-Universitaet Bonn *Recruiting*
Bonn, ,
Germany
Recruiting Wolfgang Caselmann
Karolinska Hospital *Recruiting*
Stockholm, ,
Sweden
Recruiting Rolf Hultcrantz 46-8-5177-5033
Monash Medical Centre *Recruiting*
Melbourne, ,
Australia
Recruiting William Sievert
Northwestern University *Recruiting*
Chicago, Illinois, 60611
United States
Recruiting Steven Flamm
VA Medical Center Iowa City *Recruiting*
Iowa City, Iowa, 52246
United States
Recruiting Warren Schmidt 319-338-0581
Hopital Das Clinicas Dafmusp *Recruiting*
Sao Paulo, ,
Brazil
Recruiting Antonio Barone 5511-30615544
Hospital clinic i Provincial *Recruiting*
Barcelona, ,
Spain
Recruiting Jose Sanchez-Tapias 34 93 227 54 99
Pepagni Hospital *Recruiting*
Heraklion, ,
Greece
Recruiting John Diamantis +30 2810 394626
University Health Network *Recruiting*
Toronto, ,
Canada
Recruiting Jenny Heathcote
Klinik fur Allgemeine und Innere Medizin der Universitat Schleswig-Holstein *Recruiting*
Kiel, ,
Germany
Recruiting Holger Hinrichsen
Vancouver General Hospital *Recruiting*
Vancouver, ,
Canada
Recruiting Frank Anderson 604-876-5122
Polilinico P. Giaccone *Recruiting*
Palermo, ,
Italy
Recruiting Antonio Craxi -6552332
Universitaetsklinik St. Josef-Hospital, Medizinische Klinik I *Recruiting*
Bochum, ,
Germany
Recruiting Wolfgang Schmidt 0049-234-509-2311
Ospedale Molinette *Recruiting*
Torino, , 10126
Italy
Recruiting Mario Rizzetto +390116336397
University of Pennsylvania *Completed*
Philadelphia, Pennsylvania, 19104
United States
Completed
Centre Universitaire de Sante Mcgill *Recruiting*
Montreal, ,
Canada
Recruiting Elliot Alpert 514-842-1231
Heritage Medical Research Clinic/University of Calgary *Recruiting*
Calgary, ,
Canada
Recruiting Kelly Burak
Westmead Hospital *Recruiting*
Westmead, New South Wales,
Australia
Recruiting Jacob George 612-9845-7705
CHU de Liege *Recruiting*
LIEGE, ,
Belgium
Recruiting Jean Delwaide 3243367256
Hopital Saint Joseph *Recruiting*
Marseille Cedex 08, ,
France
Recruiting Marc Bourliere 04 91 80 68 78
University of Cincinnati *Recruiting*
Cincinnati, Ohio, 45267
United States
Recruiting Kenneth Sherman 513-558-1900
Royal Brisbane Hospital *Recruiting*
Brisbane, ,
Australia
Recruiting Graeme Macdonald 61736368111
Hopital das Clinicas de Universidade Federal de Minas Garais *Recruiting*
Belo Horizonte MG, ,
Brazil
Recruiting Joao Filho 5531-32489746
A.P.H. Paris, Hopsital Pitie-Salpetriere *Recruiting*
Paris, , 75651
France
Recruiting Thierry Poynard 01-42-16-10-02
Hospital 12 de Octubre *Not yet recruiting*
Madrid, ,
Spain
Not yet recruiting Gregorio Castellano 34 91 390 86 26
Glasgow Royal Infirmary *Recruiting*
Glasgow, ,
United Kingdom
Recruiting John Morris 01412114000
Institut fuer klinische Pharmakologie *Recruiting*
BERN, ,
Switzerland
Recruiting Jurg Reichen 41316323191
Hospital Italiano-Sociedad Italiana De Beneficenci *Recruiting*
Buenos Aires, ,
Argentina
Recruiting Adrian Gadano 54 11 4958 1493
Alfred Hospital *Recruiting*
Melbourne, Victoria,
Australia
Recruiting Stephen Pianko 613-9276-2223
Medizinische Hochschule Hannover *Recruiting*
Hannover, ,
Germany
Recruiting Michael Manns 0049-511-532-3305
Rheinische Friedrich-Wilhelms-Universitaet Bonn *Not yet recruiting*
Bonn, ,
Germany
Not yet recruiting Ulrich Spengler
Hospital Germans Trias i Pujol *No longer recruiting*
Barcelona, ,
Spain
No longer recruiting
Sanatorio Municipal Julio A. Mendez (IMOS) *Recruiting*
Buenos Aires, ,
Argentina
Recruiting Leonardo Pinchuk 5411-4901-4697
Hospital Universitario Virgen del Rocio *Recruiting*
Sevilla, ,
Spain
Recruiting Jose Reina
Kaiser Permanente *Recruiting*
Sacramento, California, 95825
United States
Recruiting Mary Pauly 916-973-5963
John Hunter Hospital *Not yet recruiting*
Newcastle, ,
Australia
Not yet recruiting Robert Batey 612-4921-3478
Sint Jan *No longer recruiting*
Brugge, ,
Belgium
No longer recruiting
Princess Alexandra Hospital *Recruiting*
Brisbane, ,
Australia
Recruiting Darrell Crawford 617-3240-2613
Hospital das Clinicas da Universidade de Goias *Recruiting*
Goiania - GO, ,
Brazil
Recruiting Heitor Rosa 5562-2617183
Louisiana State University *Recruiting*
New Orleans, Louisiana, 70115
United States
Recruiting Luis Balart 504-899-8047
Hospital Britanico *Recruiting*
Buenos Aires, ,
Argentina
Recruiting Luis Colombato 54 11 4825 0500
Hopital Saint Luc - UCL *Recruiting*
BRUXELLES, ,
Belgium
Recruiting Yves Horsmans 32-2-764-1535
Instituto de Infectologia Emilio Ribas *Recruiting*
Sao Paulo, ,
Brazil
Recruiting Roberto Focaccia 551130883602
Clinica Puerta de Hierro *Recruiting*
Madrid, ,
Spain
Recruiting Jose Calleja 629063262
Hospital Central de Aaturias *Recruiting*
Oviedo, ,
Spain
Recruiting R. Alvarez 34 985235291
Hospices Civils de Lyon, Hotel Dieu *Recruiting*
Lyon, ,
France
Recruiting Christian Trepo 0472-413089
King's College Hospital *Completed*
London, ,
United Kingdom
Completed
Hospital de Clinicas da UFPR *Recruiting*
Curitiba, ,
Brazil
Recruiting Dominique Muzzillo 5541-3601800
Hospital Saint Joseph *Recruiting*
Marseille, ,
France
Recruiting Marc Bouliere 0491806912
Freeman Hospital *Recruiting*
Newcastle upon Tyne, ,
United Kingdom
Recruiting Margaret Bassendine 0191 223 3111
Unidad de Investigacion de Gastoenterologia *Recruiting*
San Juan, ,
Puerto Rico
Recruiting Esther Torres 787 754 0101
Southhampton General Hospital *Recruiting*
Southampton, ,
United Kingdom
Recruiting William Rosenberg 44 2380 796883
Sociedad Espanola de Beneficencia de Puebla *No longer recruiting*
Puebla, ,
Mexico
No longer recruiting
Centro Medico "20 de Noviembre"/Torre Hospital *Recruiting*
Mexico, D.F., ,
Mexico
Recruiting Mayra Ramos
Hospital Vall d'Hebron *Recruiting*
Barcelona, ,
Spain
Recruiting Rafael Esteban-Mur 34 93 274 6000
Ospedale Maggiore-IRCCS Policlinico *Recruiting*
Milan, ,
Italy
Recruiting Massimo Colombo 39 02 550 354 32
Hospital Universitario Clementino Fraga Filho *Recruiting*
Rio de Janeiro, ,
Brazil
Recruiting Henrique Coelho 5521-25622463
Hopsital Clinio Universitario de Valencia *Recruiting*
Valencia, ,
Spain
Recruiting Miguel Serra-Desfillis 34963862600
National Taiwan University Hospital *Recruiting*
Taipei, ,
Taiwan, Province of China
Recruiting Ming-Yang Lai 886 2 23123456
Hospital Universitario Gaffree & Guinle *Recruiting*
Rio de Janeiro - RJ, ,
Brazil
Recruiting Carlos Mello 5521/2240-4878
D.I.M.I Universita Di Genova *Recruiting*
Genova, ,
Italy
Recruiting Antonino Picciotto 39 010 35 38 992
Walter Mackenzie HSC - 2E1.16 *Recruiting*
Edmonton, ,
Canada
Recruiting Klaus Gutfreund 780-407-7603
C.H.U de Nancy, Hopital de Brabois Adultes *Recruiting*
Vandouevre les Nancy, ,
France
Recruiting Jean-Pierre Bronowicki 03 83 15 36 61
Hospital Universitario de la Princesa *Recruiting*
Madrid, ,
Spain
Recruiting Ricardo Moreno-Otero 34 91 309 39 11
Instituto Nacional De Ciencias Medicas Y Nutricion *Recruiting*
Mexico, ,
Mexico
Recruiting David Kershenobich-Stalnikowitz 5255-5537-1200
Additional Information:
Study ID Numbers: P02370;
Study Start Date:
Record last reviewed: January 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00039871
Other Cirrhosis Studies:
1. Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis
2. Prevention of Disease Progress in Chronic HepC Pts Significant Liver Fibrosis who failed PEG-Intron + Rebetol in P02370
3. PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin
Related Studies:
Other Cirrhosis Clinical Trials
Other Clinical Trials
Other Milan Clinical Trials
PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin
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