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ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence



ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence

For Condition: Diabetes,Urinary Incontinence
Status: Recruiting
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) , University of California, San Francisco
Synopsis: This study consists of two studies with overlapping cohorts. One is a follow up epidemiological study of urinary incontinence, the other is a case control study of lower urinary tract dysfunction in women with diabetes. Study One: Subjects for the study will be a retrospective cohort of 2100 middle-aged and older women from a large health maintenance organization who have participated in the Reproductive Risk Factor for Incontinence Study at Kaiser (RRISK). The RRISK I study assembled a retrospective cohort of long-term female Kaiser Permanente members to determine the association between specific childbirth events, hysterectomy, hormone use and urinary incontinence later in life. The study also provides descriptive information on urinary incontinence by type, age, ethnicity, severity and age of onset. Study Two: Women with diabetes have a 30-70% increased risk of lower urinary tract dysfunction, including lower urinary tract symptoms, urinary incontinence, and ultimately bladder cystopathy. This sudy investigates the natural history, risk factors, and possible mechanisms of lower urinary tract dysfunction and infection among women with type 2 diabetes as compared to women without diabetes.
Details:
Eligibility:
Study Type:
  Observational, Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study
Minimum Age/Maximum Age: 44 Years/73 Years
Genders: Female
Protocol Entry Criteria: - Previous participation in the Reproductive Risk Factors for Incontinence Study at Kaiser. - Women aged 40-69 on 1/1/99 who have been Kaiser Permanente members since age 18 and have had half or more of their deliveries at Kaiser Permanente or are nulliparous and have diabetes.
Total Enrollment: 2350

Location and Contact Information:

Kaiser Permanente, Northern California, Division of Research *Recruiting*
Oakland,  California,  94612
United States
Recruiting Arona  Ragins 510-891-3748


Additional Information:
Study ID Numbers:
  ORSCOR; 
Study Start Date: July 2003
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00069368

Other Urinary Incontinence Studies:
1. ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence

2. Prevent Inability To Control Urination

3. Randomized Clinical Trial of Burch vs Sling Procedures for Women with Stress Urinary Incontinence

4. A Case Finding and Referral System for Older Veterans within Primary Care

5. An Implantable Microstimulator for the Chronic Treatment of Refractory Urinary Urge Incontinence

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