|
Nocturnal Oxygen Therapy Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or professional assistance by using a genuine doctor. We aren't mDs. Always consult your physician about Nocturnal Oxygen Therapy conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Nocturnal Oxygen Therapy Clinical research trials and Nocturnal Oxygen Therapy health trials occur in a lot of of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the potency of new does drugs. The role of the studies / undertakings is to figure out specific human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Nocturnal Oxygen Therapy. Nocturnal Oxygen Therapy Clinical Trials and other clinical trials permit volunteers to get medical treatment choices before they are available to the general public. Many times the test subjects get professional assistance for free of charge, and occasionally they are compensated for their time. Sometimes there is a cost for a Nocturnal Oxygen Therapy clinical trial. Human subjects often get the best healthcare possible for their Nocturnal Oxygen Therapy condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, medical hazards (perhaps life-threatening), and/or the treatment being ineffectual. Trials are federally governed with exacting guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "N" Clinical Trials Conditions > Nocturnal Oxygen Therapy  Nocturnal Oxygen Therapy
Nocturnal Oxygen Therapy
For Condition: Lung Diseases,Lung Diseases, Obstructive,Chronic Obstructive Pulmonary Disease
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: To compare the efficacy of long-term use of nocturnal oxygen therapy (12 hours) with that of continuous, low-flow oxygen therapy (24 hours) in patients with chronic hypoxic lung disease.
Details: BACKGROUND: Chronic obstructive pulmonary disease is a major health problem in the United States. In 1975, it was the sixth leading cause of death. The economic impact of the disease in 1972 amounted to $803 million in the direct costs of disability treatment, $3.05 billion in disability costs, and $645 million in lost earnings due to premature death. Motivated in part by the significant toll of this disease, a conference on the Scientific Basis of Respiratory Therapy, co-sponsored by the American Thoracic Society and the Division of Lung Diseases, examined the current status of the use of oxygen therapy in chronic lung disease. The proceedings of the conference, published in the American Review of Respiratory Disease (Vol. 110, No. 6, December 1974), included a recommendation for clinical studies that would provide a critical assessment of the role of nocturnal oxygen therapy in the treatment of patients with chronic obstructive pulmonary disease. Low-flow oxygen, administered continuously, was known to benefit some patients with chronic hypoxic lung disease. However, low-flow oxygen administration for long periods of time is cumbersome, confining, and expensive. If nocturnal oxygen administration could be unequivocally demonstrated to be efficacious, then the advantages of convenience and cost would have a favorable impact on treatment of patients, and a rationale could be developed for testing this therapy in a larger group of patients. The Planning Phase of the trial was initiated in September 1976. Patient recruitment began in May 1977. The Recruitment Phase lasted 24 months. The 203 patients in the trial were assigned randomly to nocturnal oxygen therapy (home) or continuous low-flow oxygen therapy. DESIGN NARRATIVE: Randomized, fixed sample. Two hundred and three patients were randomly assigned to at-home treatments of continuous oxygen therapy or nocturnal oxygen therapy. Endpoints related to quality of life, neuropsychological function, and respiratory function and capacity. Intervention lasted for 6 months to 3 years, with an average intervention of 19.3 months.
Eligibility:
Study Type: Interventional, Treatment, Randomized
Minimum Age/Maximum Age: 35 Years/70 Years
Genders: Both
Protocol Entry Criteria: Men and women, ages 35 to 70, who had severe chronic obstructive lung disease requiring supplemental oxygen therapy.
Total Enrollment:
Location and Contact Information:
Overall Study Official:
NicholasAnthonisen, , University of Manitoba
Additional Information:
Study ID Numbers: 202;
Study Start Date: July 1976
Record last reviewed: May 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000564
Other Chronic Obstructive Pulmonary Disease Studies:
1. Inhaled NO in Prevention of Chronic Lung Disease
2. National Heart, Lung, and Blood Institute Twin Study
3. Tuberculosis Prophylaxis in the Homeless--A Controlled Trial
4. Risk Factors for Pulmonary Hypertension of the Newborn
5. Determinants of Respiratory Health in Young Adults
Related Studies:
Other Chronic Obstructive Pulmonary Disease Clinical Trials
Other Clinical Trials
Other Clinical Trials
Nocturnal Oxygen Therapy
|
|
|
|
|
|
|
|
