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Major depression and inflammatory risk markers for coronary heart disease Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for qualified medical advice, visits or professional assistance by using a real mD. We are not docs. Always confer with your physician about Major depression and inflammatory risk markers for coronary heart disease conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Major depression and inflammatory risk markers for coronary heart disease Clinical research trials and Major depression and inflammatory risk markers for coronary heart disease health trials occur in many of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectivity of new does drugs. The intent of the studies / undertakings is to resolve particular human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to detect remedies for all sorts of conditions, including Major depression and inflammatory risk markers for coronary heart disease. Major depression and inflammatory risk markers for coronary heart disease Clinical Trials and other clinical trials permit volunteers to obtain healthcare treatment alternatives before they are available to the masses. Most times the participants undergo professional assistance for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a Major depression and inflammatory risk markers for coronary heart disease clinical trial. Test subjects typically receive the most expert healthcare available for their Major depression and inflammatory risk markers for coronary heart disease condition. Dangers are a reality, however, and may include more or frequent mD visits, healthcare dangers (perhaps life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with rigid guidelines to protect clinical trials patients.
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Home > "M" Clinical Trials Conditions > Major depression and inflammatory risk markers for coronary heart disease  Major depression and inflammatory risk markers for coronary heart disease
Major depression and inflammatory risk markers for coronary heart disease
For Condition: Depression
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) , American Heart Association
Synopsis: The overall purpose of this research is to examine whether depression influences immune system function. Studies indicate that individuals who are depressed experience coronary heart disease at a higher rate than expected. This study's goal is to begin identifying mechanisms that might be responsible for this process. This research also examines whether behavioral processes (e.g. smoking) or hormonal processes (e.g. adrenaline release) are responsible for immune system differences between depressed and nondepressed people
Details: To qualify for participation, subjects are to be between the ages of 18-55, medically healthy and free of all medication three months prior to enrollment. Half of them will be clinically depressed; the remaining one half will be healthy controls without a history of psychiatric illness. All subjects who qualify for the study will attend two laboratory sessions. During the first visit, participants will undergo a structured psychological interview, complete questionnaires about their mood, personality, and behavior, and have blood drawn to assess their immune system function. During the second visit, participants will complete additional questionnaires about their mood, personality, and behavior. The subjects will also participate in a mock job interview to look at their body's response to stress. Before and after the interview, the subjects will have blood drawn and be asked to collect saliva samples to assess their immune system function. In addition to the two laboratory visits, participants will be asked to collect additional information while going about their normal activities. In order to accomplish this, they will be given a small hand held portable computer. Four times each day for four days, the computer will signal them to collect a saliva sample. This will be used later to measure hormone levels. This study will explore changes in the immune system and metabolic system that might predispose depressed individuals to develop heart disease
Eligibility:
Study Type: Observational, Natural History, Cross-Sectional, Defined Population, Prospective Study
Minimum Age/Maximum Age: 15 Years/55 Years
Genders: Both
Protocol Entry Criteria: For eligibility, potential subjects will be 18-55 years of age, free of all medication during the past three months, and have no history of chronic illness involving the cardiovascular, endocrine, immune systems
Total Enrollment:
Location and Contact Information:
Washington University
St. Louis, Missouri, 63130
United States
Additional Information:
Study ID Numbers: NCRR-M01RR00036-0849;
Study Start Date:
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00037505
Other Depression Studies:
1. Anxiety and Vagal Control of the Heart in Coronary Disease
2. Transcranial magnetic stimulation in depression
3. Women's Use of Alternative Medicine: A Multiethnic Study
4. Duloxetine vs. active comparator for the treatment of depression
5. Depression and Health Outcomes in Refractory Epilepsy
Related Studies:
Other Depression Clinical Trials
Other Missouri Clinical Trials
Other St. Louis Clinical Trials
Major depression and inflammatory risk markers for coronary heart disease
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