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Long Term Follow-Up of Diabetic Retinopathy Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Long Term Follow-Up of Diabetic Retinopathy conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Long Term Follow-Up of Diabetic Retinopathy Clinical research trials and Long Term Follow-Up of Diabetic Retinopathy health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Long Term Follow-Up of Diabetic Retinopathy. Long Term Follow-Up of Diabetic Retinopathy Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Long Term Follow-Up of Diabetic Retinopathy clinical trial. Participants oftentimes recieve the most expert healthcare available for their Long Term Follow-Up of Diabetic Retinopathy condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "L" Clinical Trials Conditions > Long Term Follow-Up of Diabetic Retinopathy  Long Term Follow-Up of Diabetic Retinopathy
Long Term Follow-Up of Diabetic Retinopathy
For Condition: Blindness,Cataract,Diabetes Mellitus,Diabetic Retinopathy,Macular Degeneration
Status: Completed
Sponsor(s): National Eye Institute (NEI) ,
Synopsis: The efficacy of laser photocoagulation treatment for diabetic retinopathy has been demonstrated by several National Eye Institute (NEI) sponsored clinical trials. The Diabetic Retinopathy Study (DRS) demonstrated that scatter photocoagulation reduces the risk of blindness from diabetic retinopathy. The Early Treatment Diabetic Retinopathy Study (ETDRS) extended these findings by providing information on when to initiate scatter photocoagulation and by demonstrating that focal treatment was effective in treating macula edema. The Krypton Argon Regression Neovascularization Study (KARNS) showed that scatter photocoagulation with krypton red laser was just as safe and effective as the argon blue-green laser in the treatment of proliferative diabetic retinopathy. Unfortunately, there is little data on the long term effects of photocoagulation on visual function. The first objective of this study is to assess the long term effects of photocoagulation for diabetic retinopathy. A second objective is to provide additional information on the risk of progression of cataracts in persons with diabetes. All patients previously treated with laser photocoagulation (focal and/or scatter) are eligible to participate in this long term study. The first priority will be given to patients who participated in the ETDRS and KARNS because of the wealth of information available regarding the details of their treatment and course after treatment. Study evaluations will include a standard ophthalmic examination, fluorescein angiography, lens and fundus photography.
Details: The efficacy of laser photocoagulation treatment for diabetic retinopathy has been demonstrated by several National Eye Institute (NEI) sponsored clinical trials. The Diabetic Retinopathy Study (DRS) demonstrated that scatter photocoagulation reduces the risk of blindness from diabetic retinopathy. The Early Treatment Diabetic Retinopathy Study (ETDRS) extended these findings by providing information on when to initiate scatter photocoagulation and by demonstrating that focal treatment was effective in treating macula edema. The Krypton Argon Regression Neovascularization Study (KARNS) showed that scatter photocoagulation with krypton red laser was just as safe and effective as the argon blue-green laser in the treatment of proliferative diabetic retinopathy. Unfortunately, there is little data on the long term effects of photocoagulation on visual function. The first objective of this study is to assess the long term effects of photocoagulation for diabetic retinopathy. A second objective is to provide additional information on the risk of progression of cataracts in persons with diabetes. All patients previously treated with laser photocoagulation (focal and/or scatter) are eligible to participate in this long term study. The first priority will be given to patients who participated in the ETDRS and KARNS because of the wealth of information available regarding the details of their treatment and course after treatment. Study evaluations will include a standard ophthalmic examination, fluorescein angiography, lens and fundus photography.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: All patients with diabetic retinopathy that has been treated previously with laser photocoagulation, either focal or scatter treatment, are eligible. Patients must be 18 or more years of age. Patients who have not had laser photocoagulation for diabetic retinopathy are not eligible for the study.
Total Enrollment: 75
Location and Contact Information:
National Eye Institute (NEI)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 940106; 94-EI-0106
Study Start Date: March 10, 1994
Record last reviewed: March 24, 1999
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001395
Other Macular Degeneration Studies:
1. Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis
2. Age-Related Macular Degeneration and Cataract
3. Clinical and Genetic Studies of Families with Congenital or Hereditary Cataracts
4. Pilot Study: Dynamic Light Scattering Device for Studying Early Changes in Cataract
5. Studies of Families with Hereditary Cataracts
Related Studies:
Other Macular Degeneration Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Long Term Follow-Up of Diabetic Retinopathy
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