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Lifestyle interventions to reduce diabetes risk



Lifestyle interventions to reduce diabetes risk

For Condition: Glucose Intolerance,Diabetes Mellitus, Type 2
Status: Completed
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ,
Synopsis: Type 2 diabetes is more frequent in Japanese Americans than in Japan or the U.S. non-Hispanic white population. This appears to be due to the effects of ''westernization'' to bring out metabolic changes that lead to diabetes. This study will look at whether increased physical activity and dietary changes will reduce or prevent the metabolic changes that lead to type 2 diabetes in Japanese Americans who have impaired glucose tolerance, a condition intermediate between normal glucose tolerance and diabetes.
Details:
Eligibility:
Study Type:
  Interventional, Prevention, Randomized, Placebo Control
Minimum Age/Maximum Age: 40 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Japanese American - Confirmed impaired glucose tolerance - Able to fill out questionnaires Exclusion Criteria: - Significant exercise-restricting disease - Poorly controlled hypertension - Psychiatric disease or dementia - Already on unusually restrictive diet - Use of hypolipidemic drugs - Use of tobacco - Abnormal blood screening tests - ECG evidence of ischemic heart disease at rest - Abnormal maximal Bruce treadmill test
Total Enrollment: 

Location and Contact Information:

University of Washington
Seattle,  Washington,  98195
United States
 


Additional Information:
Study ID Numbers:
  fujimotow;  1R01DK48152
Study Start Date: October 1994
Record last reviewed: July 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00006162

Other Glucose Intolerance Studies:
1. Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients

2. Computer-assisted diabetes self-management interventions

3. Lifestyle interventions to reduce diabetes risk

4. Effect of AC2993 Compared with Insulin Glargine in Patients with Type 2 Diabetes Also Using Combination Therapy with Sulfonylurea and Metformin

5. Improving Medication Adherence in Co morbid Conditions

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