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IUdR/BUdR cell cycle labelling



IUdR/BUdR cell cycle labelling

For Condition: Hematologic Malignancies
Status: Terminated
Sponsor(s): M.D. Anderson Cancer Center ,
Synopsis: To determine cell cycle parameters and changes after treatment, the labelling agent is given and a bone marrow aspiration is accomplished before treatment and after treatment for comparison. Participants must be undergoing concurrent therapy for hematologic malignancy.
Details: Cell cycle parameters include LI, Ts, Tc, T dpot, changes in these parameters, and differences between normal and leukemic cells in patients with hematologic malignancy prior to and following treatment.
Eligibility:
Study Type:
  Interventional, Diagnostic, Non-Randomized, Open Label, Single Group Assignment, Pharmacodynamics Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Histologic proof of one of: - AML, ALL, or AUL - MDS or CMML - CML - OR undergoing bone marrow transplantation. Participants should be: - off therapy for at least two weeks - At least 18 years old or older - Using adequate contraception if of child-bearing capability.
Total Enrollment: 180

Location and Contact Information:

Overall Study Official:
MichaelAndreeff,  Study Chair,  U. T. M. D. Anderson Cancer Center

M.D. Anderson Cancer Center
Houston,  Texas,  77030
United States
 


Additional Information:
Study ID Numbers:
  DM91-102; 
Study Start Date: October 1991
Record last reviewed: January 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00042250

Other Hematologic Malignancies Studies:
1. Phase I Study of Continuous Infusion Schedule of FMdC in Hematologic Malignancies

2. Stem Cell Transplant for Patients with Hematologic Malignancy Using Family Donors and Conditioning with Campath-1H

3. IUdR/BUdR cell cycle labelling

Related Studies:

Other Hematologic Malignancies Clinical Trials
Other Texas Clinical Trials
Other Houston Clinical Trials

IUdR/BUdR cell cycle labelling

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