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Islet Transplantation for patients with Type 1 diabetes Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified medical advice, calls or professional assistance using a genuine dr.. We aren't physicians. Always confer with your dr. on Islet Transplantation for patients with Type 1 diabetes conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Islet Transplantation for patients with Type 1 diabetes Clinical research trials and Islet Transplantation for patients with Type 1 diabetes medical trials happen in hundreds of localities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new does drugs. The intent of the studies / undertakings is to answer particular human health questions. Clinical trials are a popular manner for physicians, government agencies, and private sector corporations to find cures for all kinds of circumstances, like Islet Transplantation for patients with Type 1 diabetes. Islet Transplantation for patients with Type 1 diabetes Clinical Trials and other clinical trials permit volunteers to acquire healthcare treatment options before they are available to the general public. Some times the subjects acquire professional assistance for free, and sometimes they are paid for their time. Sometimes there is a cost for a Islet Transplantation for patients with Type 1 diabetes clinical trial. Participants frequently obtain the most expert healthcare available for their Islet Transplantation for patients with Type 1 diabetes condition. Dangers are a reality, nevertheless, and can include more or frequent doctor calls, health risks (potentially life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.

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Islet Transplantation for patients with Type 1 diabetes



Islet Transplantation for patients with Type 1 diabetes

For Condition: Diabetes Mellitus, Type 1
Status: Recruiting
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ,
Synopsis: This protocol will test whether Type 1 diabetes (T1DM) can be reversed in patients with stable renal allografts by islet transplantation.
Details: We will test whether pancreatic islets isolated from cadaveric human donor pancreata can be transplanted into the portal vein of patients with T1DM who have stable renal allografts to achieve insulin independence for the recipient. The protocol will employ a defined islet isolation procedure, percutaneous islet infusion into the recipient's portal vein via an intra-portal catheter, tight glycemic control during the peri-transplant period, and an immunosupperesive protocol that avoids glucocorticoids.
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Patients with type 1 diabetes with stable renal allografts
Total Enrollment: 10

Location and Contact Information:

Overall Study Official:
MarkHardy,  Principal Investigator,  Columbia Presbyterian Hospital

Columbia Presbyterian Medical Center *Recruiting*
New York City,  New York,  10032
United States
Recruiting Kevan  Herold 212-342-3253


Additional Information:
Study ID Numbers:
  9903; 
Study Start Date: August 2003
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00073281

Other Diabetes Mellitus, Type 1 Studies:
1. Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus

2. The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1)

3. Safety and Efficacy of Human Insulin Inhalation Powder in Patients with Type 1 Diabetes Mellitus.

4. Evaluation of the Effect of Pramlintide on Satiety and Food Intake

5. Islet Transplantation for patients with Type 1 diabetes

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