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Immunotherapy with Autologous Dexosomes for Patients with Stage IV Melanoma



Immunotherapy with Autologous Dexosomes for Patients with Stage IV Melanoma

For Condition: Melanoma
Status: Suspended
Sponsor(s): Anosys ,
Synopsis: The objective is to determine the safety and efficacy of dexosome immunotherapy in patients with Stage IV malignant melanoma
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - Patients with Stage IV metastatic melanoma with 0-1 prior treatments for metastatic disease. - All patients must have distant skin, subcutaneous, or nodal metastases (M1a) or lung metastases (M1b), measurable disease, normal lactate dehydrogenase levels, and HLA type A1, A2, or B35. - Patients must have adequate organ function and an estimated life expectancy of at least 3 months.
Total Enrollment: 60

Location and Contact Information:


Additional Information:
Study ID Numbers:
  AN2002-04; 
Study Start Date: July 2002
Record last reviewed: September 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00042497

Other Melanoma Studies:
1. Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

2. ADI-PEG in Patients With Metastatic Melanoma

3. Vaccine Therapy and Interleukin-12 With Either Alum or Sargramostim After Surgery in Treating Patients With Melanoma

4. A Phase I Study of Intralesional Administration of an Adenovirus Vector Expressing the HSV-1 Thymidine Kinase Gene (AdV.RSV-TK) in Combination with Escalating Doses of Ganciclovir in Patients with Cutaneous Metastatic Malignant Melanoma

5. gp100 and MDX-010 Vaccination for Stage IV Melanoma

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