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Healthy Aging and Memory Study



Healthy Aging and Memory Study

For Condition: Alzheimer Disease
Status: No longer recruiting
Sponsor(s): National Institute on Aging (NIA) ,
Synopsis: This project will focus on the development and testing of efficient, cost effective measures that are specifically designed for use in Alzheimer's Disease (AD) primary prevention trials.
Details: This project will focus on the development and testing of efficient, cost effective measures that are specifically designed for use in AD primary prevention trials. The new or improved measures that have been developed will then be evaluated in 650 nondemented subjects enrolled in a simulated Alzheimer's disease prevention trial. Once enrolled, subjects will be followed for four years with annual clinical evaluations and interim six-month phone calls.
Eligibility:
Study Type:
  Observational, Screening, Longitudinal, Defined Population, Prospective Study
Minimum Age/Maximum Age: 75 Years/
Genders: Both
Protocol Entry Criteria: - 75 years or older. - Fluent in English or Spanish. - Stable medical condition for four weeks prior to screening visit. - Stable medications for four weeks prior to screening visit. - Either cognitively normal, or mild cognitive impairment. If MCI, the subject's CDR at screening have a global score of 0.5. - mMMSE score greater than 88 for subjects with at least 8 years education, or greater than 80 for subjects with less than 8 years education, and FCSRT total free plus cued recall score greater than 44 with 3 learning trials. - Willing to participate in four to five year follow-up study. - Willing to identify person who can serve as informant. - At least six years education or work history sufficient to exclude mental retardation
Total Enrollment: 650

Location and Contact Information:

Overall Study Official:
StevenFerris,  Study Director,  New York University School of Medicine

Stanford/Va Aging Clinical Research Center
Palo Alto,  California,  94304
United States
 

Baumel-Eisner Neuromedical Institute, Miami Beach
Miami,  Florida,  33154
United States
 

University of California, Davis
Sacramento,  California,  95817
United States
 

Medical University of South Carolina
North Charleston,  South Carolina,  29406
United States
 

Georgetown University Medical Center
Washington D.C.,  District of Columbia,  20007
United States
 

University of California, Los Angeles
Los Angeles,  California,  90095-1769
United States
 

Emory University
Atlanta,  Georgia,  30329
United States
 

Northwestern University
Chicago,  Illinois,  60611
United States
 

Columbia University
New York City,  New York,  10032
United States
 

Washington University
St. Louis,  Missouri,  63108
United States
 

University of Nevada, Las Vegas
Las Vegas,  Nevada,  89102
United States
 

Indiana University Alzheimer's Center
Indianapolis,  Indiana,  46202
United States
 

New York University School of Medicine
New York City,  New York,  10016
United States
 

University of Pittsburgh
Pittsburgh,  Pennsylvania,  15213
United States
 

Baumel-Eisner Ft Lauderdale
Ft. Lauderdale,  Florida,  33321
United States
 

Michigan Alzheimer's Disease Research Center
Ann Arbor,  Michigan,  48109-2007
United States
 

Mt. Sinai Medical Center
New York City,  New York,  10029
United States
 

Oregon Health Sciences University
Portland,  Oregon,  97201
United States
 

Sun Health Research Institute
Sun City,  Arizona,  85351
United States
 

Brigham and Women's Hospital
Boston,  Massachusetts,  02115
United States
 

University of Alabama, Birmingham
Birmingham,  Alabama,  35294-1150
United States
 

Rush Alzheimer's Disease Center
Chicago,  Illinois,  60612
United States
 

Baumel-Eisner Neuromedical Institute, Boca Raton
Boca Raton,  Florida,  33486
United States
 

Boston University School of Medicine
Boston,  Massachusetts,  02118
United States
 

University of South Florida, Tampa
Tampa,  Florida,  33617
United States
 

University of Rochester
Rochester,  New York,  14620
United States
 

University Hospitals of Cleveland
Cleveland,  Ohio,  44120-1013
United States
 

University of Pennsylvania
Philadelphia,  Pennsylvania,  19104
United States
 

Memorial Hospital of Rhode Island (Brown University)
Pawtucket,  Rhode Island,  02860
United States
 

Mayo Clinic, Jacksonville
Jacksonville,  Florida,  32224
United States
 

Johns Hopkins University
Baltimore,  Maryland,  21287-7218
United States
 

University of California, San Diego
La Jolla,  California,  92037
United States
 

Yale University School of Medicine
New Haven,  Connecticut,  06510
United States
 

University of Texas Southwestern Medical Center
Dallas,  Texas,  75390-9070
United States
 

University of Kentucky, Lexington
Lexington,  Kentucky,  40506
United States
 

Mayo Alzheimer's Disease Center
Rochester,  Minnesota,  55901
United States
 

University of Southern California
Los Angeles,  California,  90033-1039
United States
 

Wien Center for Memory Disorders
Miami,  Florida,  33140
United States
 

University of California, Irvine
Irvine,  California,  92697-4285
United States
 


Additional Information:
Study ID Numbers:
  IA0032; 
Study Start Date: 
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00034567

Other Alzheimer Disease Studies:
1. Multicenter Trial of Prednisone in Alzheimer's Disease

2. The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease

3. Valproate in Dementia (VALID)

4. Effectiveness of A Nutritional Brain Metabolic Enhancer for Alzheimer Disease

5. The Depression in Alzheimer's Disease Study (DIADS)

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