Search Clinical Trials
 
By Condition
 
By Location (USA)
 
By Location (Other)
 
By Sponsor
 
Resources
 
Privacy Policy
 
About Us
Disclaimer
Genetic Analysis of Familial Brain Aneurysms Clinical Trials Information presented on Clinical Trials Search isn't intended to be a substitute for proven healthcare advice, trips or treatment using a real physician. We are not docs. Always confer with your mD on Genetic Analysis of Familial Brain Aneurysms conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Genetic Analysis of Familial Brain Aneurysms Clinical research trials and Genetic Analysis of Familial Brain Aneurysms medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectiveness of new drugs. The intention of the studies / projects is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector corporations to detect remedies for all forms of circumstances, like Genetic Analysis of Familial Brain Aneurysms. Genetic Analysis of Familial Brain Aneurysms Clinical Trials and other clinical trials allow for volunteers to undergo healthcare treatment options before they are available to the masses. Most times the participants receive treatment for free, and every now and again they are paid for their time. Occasionally there is a cost for a Genetic Analysis of Familial Brain Aneurysms clinical trial. Subjects typically recieve the finest healthcare available for their Genetic Analysis of Familial Brain Aneurysms condition. Hazards are a reality, nonetheless, and might include more or frequent mD trips, health risks (potentially life-endangering), and/or the treatment being ineffective. Trials are federally regulated with stern guidelines to protect clinical trials subjects.

Home > "G" Clinical Trials Conditions > Genetic Analysis of Familial Brain Aneurysms

Genetic Analysis of Familial Brain Aneurysms



Genetic Analysis of Familial Brain Aneurysms

For Condition: Intracranial Aneurysm
Status: Completed
Sponsor(s): National Human Genome Research Institute (NHGRI) ,
Synopsis: This study will investigate cerebral (brain) aneurysms and their possible inheritance patterns in families. It will try to determine how often brain aneurysms occur in families in which more than one member has had an aneurysm and to find the gene or genes that contribute to their development. People in families in which more than one family member had a cerebral aneurysm are eligible for this 1-day study. They will undergo the following procedures: - Blood will be drawn (no more than 3 to 4 tablespoons) for research to identify genes that contribute to the development of brain aneurysms. - A magnetic resonance angiograph (MRA) scan will be done to examine a specific brain area where aneurysms typically occur. Magnetic resonance imaging uses a strong magnetic field and radio waves to produce images of the brain and detect abnormalities. If a more detailed picture of the brain is needed than can be obtained with MRA, a more specific MRA scan will be done using a contrast dye to enhance the images. Patients may be invited to participate in related NIH research studies.
Details: This study is designed to explore the genetics of familial cerebral aneurysms. Families in which more than one person has had a known cerebral aneurysm will be studied. Family histories will be obtained and participants identified who are willing to come to the NIH Clinical Center for an MRAngiograph and venipuncture. DNA will be isolated and linkage studies undertaken to identify loci involved in the etiology of familial cerebral aneurysms, using standard linkage approaches.
Eligibility:
Study Type:  Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Participants and their relatives that are affected or at a higher risk for cerebral aneurysms will be enrolled in this protocol. EXCLUSION CRITERIA: For the MR Angiograph portion of the study, any participant that is not able to sign the Clinical Center consent form due to metal implants, pregnancy, claustrophobia, or an allergy to gadolinium as a contrast will be excluded from the imaging part of the study.
Total Enrollment: 300

Location and Contact Information:

National Human Genome Research Institute (NHGRI)
Bethesda,  Maryland,  20892
United States
 


Additional Information:
Study ID Numbers:  010101;  01-HG-0101
Study Start Date: February 22, 2001
Record last reviewed: March 22, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00011856

Other Intracranial Aneurysm Studies:
1. Familial Intracranial Aneurysm Study

2. Genetic Analysis of Familial Brain Aneurysms

Related Studies:

Other Intracranial Aneurysm Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials

Genetic Analysis of Familial Brain Aneurysms
Modify your Search

  Other Intracranial Aneurysm Clinical Trials
  Other Maryland Clinical Trials
  Other Bethesda Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103