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Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer Clinical Trials Info presented on Clinical Trials Search is not intended to be a substitute for certified medical advice, visits or professional assistance using a real physician. We are not physicians. Always consult your dr. about Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer Clinical research trials and Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer health trials happen in many of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new drugs. The function of the studies / projects is to resolve particular human medical questions. Clinical trials are a popular manner for mDs, government agencies, and private sector corporations to discover remedies for all varieties of circumstances, like Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer. Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer Clinical Trials and other clinical trials allow volunteers to obtain healthcare treatment options before they are available to the masses. Some times the participants undergo professional assistance for free of charge, and occasionally they are paid for their time. Sometimes there is a cost for a Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer clinical trial. Human subjects often get the best healthcare available for their Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer condition. Dangers are a reality, however, and may include additional or frequent mD visits, healthcare dangers (potentially life-jeopardising), and/or the treatment being ineffectual. Trials are federally governed with rigorous guidelines to protect clinical trials patients.

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Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer



Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer

For Condition: Ovarian Cancer,Peritoneal Cancer
Status: Suspended
Sponsor(s): Eli Lilly and Company ,
Synopsis: This study hopes to evaluate whether the combination of Gemzar plus Alimta will have any beneficial effects for patients with recurrent platinum-sensitive or platinum-resistant ovarian or peritoneal cancer. Treatments are weekly for two weeks, with the 3rd week off and will be repeated every 21 days. Side effects and the overall safety of the treatment will also be monitored and evaluated. In addition, a Quality of Life questionnaire is part of this study to help measure patient perceived benefits or drawbacks to this treatment regimen.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Female
Protocol Entry Criteria: Inclusion Criteria: - Patients must have disease that can be measured. - Patients must meet criteria for either platinum-resistant or platinum-sensitive ovarian or peritoneal cancer. - Patients may only have had one prior platinum-based chemotherapy regimen. - Patients must be willing and able to stop all aspirin and NSAID medications immediately before and for a time after each treatment cycle (approx. 5-8 days) - Patients must have normal kidney function. Exclusion Criteria: - Patients may not have a Low Malignant Potential or Borderline Ovarian Tumor. - Patients may not have received pelvic or abdominal radiotherapy. - Patients must not have evidence of or received treatment for another cancer within the last 5 years. - Patients must not have been diagnosed with a heart attack in the last 6 months. - Patients who are unwilling or unable to take folic acid tablets, vitamin B12 injections or dexamethasone tablets.
Total Enrollment: 

Location and Contact Information:

For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician.
Atlanta,  Georgia, 
United States
 


Additional Information:
Study ID Numbers:
  7127; 
Study Start Date: 
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00055432

Other Peritoneal Cancer Studies:
1. Gemzar (gemcitabine) and Alimta (pemetrexed) in the Treatment of Patients with Recurrent Platinum-Sensitive and Platinum-Resistant Ovarian or Peritoneal Cancer

2. Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer

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