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Evaluation and Treatment of Oral Soft Tissue Diseases Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified medical advice, calls or professional assistance using a genuine dr.. We aren't physicians. Always confer with your dr. on Evaluation and Treatment of Oral Soft Tissue Diseases conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Evaluation and Treatment of Oral Soft Tissue Diseases Clinical research trials and Evaluation and Treatment of Oral Soft Tissue Diseases medical trials happen in hundreds of localities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new does drugs. The intent of the studies / undertakings is to answer particular human health questions. Clinical trials are a popular manner for physicians, government agencies, and private sector corporations to find cures for all kinds of circumstances, like Evaluation and Treatment of Oral Soft Tissue Diseases. Evaluation and Treatment of Oral Soft Tissue Diseases Clinical Trials and other clinical trials permit volunteers to acquire healthcare treatment options before they are available to the general public. Some times the subjects acquire professional assistance for free, and sometimes they are paid for their time. Sometimes there is a cost for a Evaluation and Treatment of Oral Soft Tissue Diseases clinical trial. Participants frequently obtain the most expert healthcare available for their Evaluation and Treatment of Oral Soft Tissue Diseases condition. Dangers are a reality, nevertheless, and can include more or frequent doctor calls, health risks (potentially life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
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Home > "E" Clinical Trials Conditions > Evaluation and Treatment of Oral Soft Tissue Diseases  Evaluation and Treatment of Oral Soft Tissue Diseases
Evaluation and Treatment of Oral Soft Tissue Diseases
For Condition: Aphthous Stomatitis,Burning Mouth Syndrome,Lichen Planus,Mouth Disease,Temporomandibular Joint Disorder
Status: Completed
Sponsor(s): National Institute of Dental and Craniofacial Research (NIDCR) ,
Synopsis: This study offers evaluation and treatment of patients with diseases of the mouth or systemic diseases that involve the mouth. The protocol is not designed to test new treatments; rather, patients will receive current standard of care treatments. The purposes of the study are: 1) to allow NIDCR's Gene Therapy and Therapeutics Branch staff to gain more knowledge about oral soft tissue diseases and possibly identify new avenues of research in this area; and 2) to establish a pool of patients who may be eligible for new studies as they are developed. (Participants in this protocol will not be required to join a new study; the decision will be voluntary.) Patients of any age with oral diseases or systemic diseases involving the mouth may be eligible for this study. Women of childbearing potential and women who are pregnant or breastfeeding will only have tests and procedures and receive medications that pose no greater than a minimal risk to the fetus. Participants will have a comprehensive dental and medical examination, including a physical examination of the head and neck. Additional tests and procedures that may be required for diagnosis and to guide treatment include the following: - Blood and urine tests - for routine laboratory studies, assessment of kidney and liver function, and detection of viruses, fungi, bacteria or parasites - Electrocardiogram - to record the electrical activity of the heart - Biopsies - to examine tissue under the microscope. The method and number of biopsies depends on the individual's specific condition and the tissue to be removed. For all biopsies a local anesthetic (lidocaine with or without epinephrine) is injected at the biopsy site. A punch biopsy uses a small sharp cookie-cutter instrument to remove a small (about 1/10- to 1/5-inch) piece of skin. An excisional biopsy uses a small surgical knife or scalpel to remove a piece of tissue, usually requiring some stitches to close the wound. - Diagnostic imaging - X-rays, photographs, or other tests as needed for diagnosis Treatments include tablets, injections and topically applied medications. All preparations are approved by the Food and Drug Administration and are commercially available. Patient follow-up may vary from one visit to intermittent visits over a number of years, depending on the patient's condition.
Details: The function of this protocol is to support the training of residents in Oral Medicine in the management of oral soft tissue diseases. Patients enrolled in this protocol will be evaluated and treated according to available standard procedures and therapeutic modalities. Samples of blood and oral tissues will be studied by routine and specialized investigative methods to establish the diagnoses, responses to treatment, and/or disease progression.
Eligibility:
Study Type: Interventional, Training
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA Patients of any age, both genders, and all racial/ethnic groups with oral diseases or systemic diseases with oral manifestations that will help the branch fulfill the objectives listed in Section 1.0. Women of childbearing potential, or who are pregnant or lactating, will only undergo tests and procedures, and/or receive medications for which data exists proving minimal risk to the fetus and/or child. Only diagnosis without radiographs will be performed. EXCLUSION CRITERIA A written referral is needed from the patient's physician or dentist. No patients with significant cognitive impairment. No pregnancy or lactation, if this status precludes proposed diagnostic procedures or therapies because of unknown, untoward effects on mother and/or child.
Total Enrollment: 999
Location and Contact Information:
National Institute of Dental And Craniofacial Research (NIDCR)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 970169; 97-D-0169
Study Start Date: August 13, 1997
Record last reviewed: August 26, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001601
Other Burning Mouth Syndrome Studies:
1. Evaluation and Treatment of Oral Soft Tissue Diseases
2. Thalidomide to Treat Oral Lesions in HIV-Infected Patients
Related Studies:
Other Burning Mouth Syndrome Clinical Trials
Other Maryland Clinical Trials
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Evaluation and Treatment of Oral Soft Tissue Diseases
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