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Environmental Contaminants and Infant Development



Environmental Contaminants and Infant Development

For Condition: Lead Poisoning,Mercury Poisoning
Status: Recruiting
Sponsor(s): National Institute of Environmental Health Sciences (NIEHS) , Indian and Northern Affairs, Canada,Health, Canada,Danish Institute for Public Health
Synopsis: This study is designed to examine the effects of prenatal exposure to environmental contaminants on cognitive and behavioral development and physical growth in two groups of Inuit infants-one in Northern Quebec; the other in Greenland.
Details: Due to prevailing weather patterns and ocean currents, certain environmental contaminants are transported to the Arctic region. The Inuit are among the most heavily exposed populations on earth due to the prevalence of these contaminants in traditional foods that comprise a large portion of their diet. The contaminants assessed in this study include polychlorinated biphenyls (PCBs), methylmercury, selenium, organochlorine pesticides, and lead. These contaminants are measured in umbilical cord blood samples obtained at birth, milk samples obtained from breast-feeding mothers and, in the case of mercury, hair samples obtained from the mothers. Omega-3 and omega-6 fatty acids are also assessed in these samples to examine the degree to which these nutrients may protect against adverse effects attributable to these contaminants.
Eligibility:
Study Type:
  Observational, Psychosocial, Longitudinal, Defined Population, Prospective Study
Minimum Age/Maximum Age: /1 Day
Genders: Both
Protocol Entry Criteria: infant born during recruitment period to a mother who is a resident of Povungnituk, Inukjuak, and Kuujjuarapik, Quebec or Nuuk, Greenland
Total Enrollment: 280

Location and Contact Information:

Public Health Centre of Quebec *Recruiting*
Beauport,  Quebec, 
Canada
Recruiting Gina  Muckle 418-666-7000


Additional Information:
Study ID Numbers:
  7902-CP-001; 
Study Start Date: January 1997
Record last reviewed: February 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00013858

Other Lead Poisoning Studies:
1. Lead, Endocrine Disruption and Reproductive Outcomes

2. Social Network Based Intervention to Reduce Lead Exposure among Native American Children

3. Does Lead Burden alter Neuropsychological Development?

4. Environmental Contaminants and Infant Development

5. Exposure, Dose, Body Burden and Health Effects of Lead

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