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Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis Clinical research trials and Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis. Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis clinical trial. Human subjects often receive the most effective healthcare possible for their Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "E" Clinical Trials Conditions > Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis  Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis
Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis
For Condition: Osteoarthritis, Knee
Status: Completed
Sponsor(s): Procter & Gamble Pharmaceuticals ,
Synopsis: Matrix metalloproteinases have been implicated in the cartilage degradation that occurs in osteoarthritis. PG-530742 inhibits some of these matrix metalloproteinases, thus potentially limiting cartilage degradation and disease progression. This study will test the efficacy and safety of PG-530742 in the treatment of mild to moderate knee osteoarthritis.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 40 Years/80 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - mild to moderate knee osteoarthritis confirmed by a radiographic technique. Exclusion Criteria: - secondary knee osteoarthritis; - diseases other than osteoarthritis that could cause knee pain; - any disease or intervention (surgery, intra-articular injection) that would have an impact on knee pain or mobility; - drugs that act potentially on the bone or cartilage component of the knee joint.
Total Enrollment: 375
Location and Contact Information:
The Crouch Oak Practice, 45 Station Road, Addlestone
Addlestone, Surrey, KT15 2BH
United Kingdom
Bridge House Medical Centre, Scholars Lane
Stratford-upon-Avon, Warwickshire, CV37 6HE
United Kingdom
National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology I and Metabolic Osteology, Frankel Leo u. 38-40
Budapest, , 1027
Hungary
Szent Ferenc Hospital, Department of Rheumatology, Csabai Kapu 42.
Miskolc, , 3529
Hungary
Synexus Reading Clinical Research Centre, Whiteley Glebe, 11 Glebe Road, off Christchurch Gardens
Reading, , RG2 7AG
United Kingdom
Synexus Birmingham Clinical Research Centre, Birmingham Research Park
Edgbaston, , B15 2SQ
United Kingdom
National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology and Immunology, Frankel Leo u. 38-40
Budapest, , 1027
Hungary
Rehabilitation Hospital, Gizella telep
Visegrad, Gizella telep, 2026
Hungary
Rheumatology Department, Fourth Floor, Thomas Guy House, St Guy's House
London Bridge, , SE1 9RT
United Kingdom
Dept of Rheumatology Whipps Cross University Hospital, Whipps Cross Road
London, , E11 1NR
United Kingdom
Grosvenor Medical Centre Clinical Trials Unit, 18 upper Grosvenor Road, Tunbridge Wells
Kent, , TN 1 2DX
United Kingdom
Dept of Rheumatology Dulwich Hospital, East Dulwich
London, , SE22 8PT
United Kingdom
Synexus Wrightington, Wrightington Hospital, Hall Lane, Awpley Bridge
Wigan, , WN6 9EW
United Kingdom
The Medical Centre, Kingston Avenue
East Horsley, Surrey, KT24 6QT
United Kingdom
Petz A. Country Hospital, Department of Rheumatology, Hid utca 2.
Gyor, Hid Utica 2, 9025
Hungary
Dept of Rheumatology Selly Oak Hospital, Raddleburn Road, Selly Oak
Birmingham, , B29 6JD
United Kingdom
National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology IV., Frankel Leo u. 38-40
Budapest, , 1027
Hungary
Hildenborough Medical Group, Trenchwood Surgery, 264 Shipbourne Road
Tonbridge, , TN10 3ET
United Kingdom
Orthopedic Clinic, Karolina ut 17
Budapest, , 1113
Hungary
Royal National Orthapaedic Hsopital, Brackley Hill
Stanmore, Middlesex, HA 7 4LP
United Kingdom
Pound Hill Surgery, 1 Crawley Lane, Pound Hill
Crawley, West Sussex, RH10 7DX
United Kingdom
95 Stanwell Road
Ashford, Middlesex, TW15 3EA
United Kingdom
St Thomas Hospital, Lambeth Place Road
London, SE17EH,
United Kingdom
Additional Information:
Study ID Numbers: 2001065;
Study Start Date: June 2002
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00041756
Other Osteoarthritis, Knee Studies:
1. The Effect of Weight Loss and Exercise on Knee Osteoarthritis
2. Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis
3. Prevention of Arthritis-Related Work Disability
4. Safety of Civamide Cream 0.075% as a Treatment in Subjects with Osteoarthritis of the Knee(s)
5. Shoe Insert Study
Related Studies:
Other Osteoarthritis, Knee Clinical Trials
Other Clinical Trials
Other Birmingham Clinical Trials
Efficacy and Safety of PG-530742 in the treatment of Mild to Moderate Knee Osteoarthritis
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