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Effects of home visits on medication adherence in children and youth with HIV



Effects of home visits on medication adherence in children and youth with HIV

For Condition: HIV Infections
Status: No longer recruiting
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: Adherence to complex medication regimens is critical to successful treatment of HIV infection. Unfortunately, adherence to medical regimens with conventional interventions averages 50% in chronic disease. We have observed that adherence barriers that were unrecognized by providers in the clinic setting have been detected during home visits. It is possible that recognition and interventions to resolve adherence barriers observed during home visits may improve adherence. This proposal will test the hypothesis that home-visits which identify previously unrecognized adherence barriers and provide support and education will increase medication adherence among children and youth with HIV infection and improve the patient/health care provider relationship. Specific aims of the study are: 1. Determine the impact of a series of home-visits on adherence to medication regimens for HIV infected youth and children. 1a. Adherence to medical regimens will be assessed before and after the series of home-visits using a self-report questionnaire and Microelectronic Monitoring System (MEMS) or in-home pill count. 1b. For each of these measures a percentage of adherence will be calculated and compared from a baseline to after the final home visit and after the six month follow up period. 2. Assess the changes in patient satisfaction from baseline to after the home-visits using a questionnaire completed by the patient/family. 3. Incorporate a pilot study to assess the changes in the provider's knowledge of the patient's family characteristics and home circumstances relevant to adherence following the home visits.
Details:
Eligibility:
Study Type:  Interventional, Educational/Counseling/Training, Single Group Assignment
Minimum Age/Maximum Age: /24 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - HIV positive - English speaking - Live in Denver metro area - Taking >=1 antiretroviral medication
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
ElizabethMcFarland,  Principal Investigator, 

The Children's Hospital
Denver,  Colorado,  80218
United States
 


Additional Information:
Study ID Numbers:  NCRR-M01RR00069-0622;  M01RR00069
Study Start Date: 
Record last reviewed: November 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00006439

Other Hiv Infections Studies:
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3. Treatment of Patients With Human Immunodeficiency Virus (HIV)-Related Chronic Diarrhea With Saccharomyces boulardii or Placebo: A Double Blind Trial

4. Dexamethasone in Cryptococcal Meningitis

5. A Study to Collect Information About HIV-Positive Pregnant Women and Their Babies

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Effects of home visits on medication adherence in children and youth with HIV
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