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Effectiveness of Binge Eating Disorder Treatments



Effectiveness of Binge Eating Disorder Treatments

For Condition: Eating Disorders
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to evaluate the long-term effectiveness of three Binge Eating Disorder (BED) treatments.
Details: BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED. Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - DSM-IV criteria for Binge Eating Disorder - Body Mass Index (BMI) between 27 and 45
Total Enrollment: 210

Location and Contact Information:

Washington University School of Medicine *Recruiting*
St. Louis,  Missouri, 
United States
Recruiting Sean  Monaghan 314-286-0070

W. Stewart Agras *Recruiting*
Stanford,  California,  94305
United States
Recruiting W.  Agras 650-723-7107


Additional Information:
Study ID Numbers:
  63863-01A1; 
Study Start Date: April 2002
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00060762

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