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Echinacea Versus Placebo Effect in Common Cold



Echinacea Versus Placebo Effect in Common Cold

For Condition: Common Cold
Status: Recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) ,
Synopsis: The design and interpretation of randomized trials is intimately connected to the use of “placeboâ€. The nature and magnitude of placebo effects, however, is very poorly understood. This study will assess and compare placebo effects and physician interaction effects within a community-acquired common cold model. The goal of this study is to assess two kinds of placebo effects and how physician interaction effects; a. The effect of receiving blinded placebo, compared to no treatment; and b. The effect of receiving open-label active Echinacea treatment compared to blinded active treatment.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 12 Years/17 Years
Genders: Both
Protocol Entry Criteria: Inclusion criteria: - Suspected or known cold - At least one of the following cold symptoms: nasal discharge, nasal congestion, sneezing, or sore throat - Enrolled in school Exclusion criteria: - Pregnancy; - Symptom duration > 36 hrs - Concurrent use of antibiotics, antivirals, nasal steroids, decongestants or antihistamines; - Anticipated need for symptom-relieving meds during cold - Autoimmune/deficiency disease - History of allergic rhinitis with current eye itching/sneezing - History of asthma w/current cough/SOB - Prior study entry - Allergy to Echinacea
Total Enrollment: 800

Location and Contact Information:

University of Wisconsin-Madison Department of Family Medicine *Recruiting*
Madison,  Wisconsin,  53706-1490
United States
Recruiting Laurie  Draheim 608-843-2653


Additional Information:
Study ID Numbers:
  R01AT1428;  BarrettB
Study Start Date: September 2003
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00065715

Other Common Cold Studies:
1. Echinacea Versus Placebo Effect in Common Cold

2. A Randomized Controlled Trial of Echinacea in Children

3. Evaluation of Echinacea for the Common Cold

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