|
Droxidopa in Treating Patients With Neurogenic Hypotension Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Droxidopa in Treating Patients With Neurogenic Hypotension conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Droxidopa in Treating Patients With Neurogenic Hypotension Clinical research trials and Droxidopa in Treating Patients With Neurogenic Hypotension healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Droxidopa in Treating Patients With Neurogenic Hypotension. Droxidopa in Treating Patients With Neurogenic Hypotension Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Droxidopa in Treating Patients With Neurogenic Hypotension clinical trial. Human subjects often obtain the finest healthcare possible for their Droxidopa in Treating Patients With Neurogenic Hypotension condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "D" Clinical Trials Conditions > Droxidopa in Treating Patients With Neurogenic Hypotension  Droxidopa in Treating Patients With Neurogenic Hypotension
Droxidopa in Treating Patients With Neurogenic Hypotension
For Condition: Orthostatic Hypotension,Shy-Drager Syndrome
Status: Recruiting
Sponsor(s): Mount Sinai Medical Center ,
Synopsis: RATIONALE: Neurogenic hypotension is a fall in blood pressure that occurs when one moves from a lying down to a standing position or after eating a meal. It causes one to feel dizzy, light headed, and weak. Neurogenic hypotension is caused by a problem in the part of the nervous system that controls such functions as heart rate and blood pressure. Droxidopa, a drug that may increase blood pressure, may be an effective treatment for neurogenic hypotension. PURPOSE: Clinical trial to study the effectiveness of droxidopa in treating patients who have neurogenic hypotension.
Details: PROTOCOL OUTLINE: Patients receive escalating doses of droxidopa or placebo for 7-14 days. Patients undergo blood pressure measurements hourly in both supine and standing positions.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 20 Years/
Genders: Both
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Orthostatic hypotension due to autonomic nervous system failure Fall in systolic blood pressure (supine to standing) of at least 20 mm Hg and diastolic blood pressure of at least 15 mm Hg AND Symptoms of hypotension such as dizziness, light-headedness, unsteadiness, dimming or blurred vision - History of syncope or near-syncope --Prior/Concurrent Therapy-- - Endocrine therapy: No concurrent adrenergics Concurrent fludrocortisone allowed - Other: Concurrent indomethacin, support garments, and high salt diets allowed
Total Enrollment:
Location and Contact Information:
Overall Study Official:
HoracioKaufmann, Study Chair, Mount Sinai Medical Center
Mount Sinai School of Medicine *Recruiting*
New York City, New York, 10029
United States
Recruiting Horacio Kaufmann 212-241-7315
Additional Information:
Study ID Numbers: 199/14180; MTS-GCO-98-243-3-NE
Study Start Date: March 1999
Record last reviewed: October 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00004478
Other Orthostatic Hypotension Studies:
1. Droxidopa in Treating Patients With Neurogenic Hypotension
Related Studies:
Other Orthostatic Hypotension Clinical Trials
Other New York Clinical Trials
Other New York City Clinical Trials
Droxidopa in Treating Patients With Neurogenic Hypotension
|
|
|
|
|
|
|
|
