|
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment by using a genuine medical doctor. We aren't mDs. Always confer with your doctor on Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer Clinical research trials and Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer healthcare trials occur in a lot of of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectivity of new does drugs. The role of the studies / undertakings is to solve specific human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to find treatments for all kinds of conditions, including Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer. Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer Clinical Trials and other clinical trials allow for volunteers to access health treatment choices before they are available to the general public. Many times the test subjects get treatment for without cost, and sometimes they are compensated for their time. Occasionally there is a cost for a Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer clinical trial. Test subjects typically receive the most effective healthcare possible for their Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer condition. Risks are a reality, nonetheless, and could include extra or frequent dr. calls, health hazards (perhaps life-jeopardizing), and/or the treatment being ineffective. Trials are federally regulated with rigid guidelines to protect clinical trials subjects.
|
|
|
|
|
|
|
Home > "C" Clinical Trials Conditions > Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer  Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
For Condition: recurrent colon cancer,adenocarcinoma of the rectum,stage 4 colon cancer,stage 3 rectal cancer,adenocarcinoma of the colon,stage 3 colon cancer,Stage 4 rectal cancer,recurrent rectal cancer
Status: No longer recruiting
Sponsor(s): National Cancer Institute (NCI) , Cancer and Leukemia Group B,National Cancer Institute of Canada,Eastern Cooperative Oncology Group,Southwest Oncology Group,North Central Cancer Treatment Group
Synopsis: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is most effective in treating advanced colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of various combination chemotherapy regimens in treating patients who have advanced, recurrent, or metastatic colorectal cancer that cannot be treated with surgery or radiation therapy.
Details: OBJECTIVES: I. Compare the time to progression in patients with locally advanced, locally recurrent, or metastatic colorectal adenocarcinoma treated with combinations of oxaliplatin, fluorouracil, leucovorin calcium, and irinotecan. II. Compare the quality of life, response rate, time to treatment failure, and overall survival in patients treated with these regimens. III. Compare the toxicity of these regimens in these patients. PROTOCOL OUTLINE: This is a randomized, multicenter study. Patients are stratified according to ECOG performance status (0-1 vs 2), prior adjuvant chemotherapy (yes vs no), prior immunotherapy (yes vs no), and age (under 65 vs 65 and over). Patients are randomized to one of three treatment arms. Only arm II remains open to accrual. Arm I (Saltz regimen): Patients receive irinotecan IV over 90 minutes followed by leucovorin calcium IV over 15 minutes and fluorouracil IV once a week for 4 weeks followed by 2 weeks of rest. Courses repeat every 6 weeks. (Arm I closed to accrual as of March 15, 2002.) Arm II (FOLFOX4 regimen): Patients receive oxaliplatin IV over 2 hours on day 1 and leucovorin calcium IV over 2 hours plus fluorouracil IV over 22 hours on days 1 and 2. Courses repeat every 2 weeks. Arm III (oxaliplatin plus irinotecan): Patients receive oxaliplatin IV over 2 hours and irinotecan IV over 30 minutes on day 1. Courses repeat every 3 weeks. (Arm III closed to accrual as of March 15, 2002.) Treatment continues in the absence of disease progression or unacceptable toxicity. Quality of life is assessed before treatment, during treatment (arm specific), and after completion of treatment. Patients are followed every 3 months for 1 year and then every 6 months for 2 years. PROJECTED ACCRUAL: A total of 825 patients (275 per arm) have been accrued for this study thus far. Additional patients are being accrued on arm II. (Arms I and III closed to accrual as of March 15, 2002.)
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders:
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Histologically or cytologically confirmed locally advanced, locally recurrent, or metastatic colorectal adenocarcinoma not curable by surgery or radiotherapy; Histological or cytological requirement waived in patients who developed radiological or clinical evidence of metastatic cancer after a prior surgical resection unless: More than 5 years has elapsed since primary surgery OR Primary cancer was stage I or II - Site of primary lesion must be or have been confirmed endoscopically radiologically, or surgically to be or have been in the large bowel - Measurable or evaluable disease - No CNS metastases or carcinomatous meningitis --Prior/Concurrent Therapy-- - Biologic therapy: Prior adjuvant immunotherapy for resected stage II-IV disease allowed if adjuvant therapy concluded at least 1 year before documentation of recurrent disease; No concurrent sargramostim (GM-CSF) - Chemotherapy: No prior chemotherapy for advanced colorectal cancer; No prior standard adjuvant chemotherapy for rectal cancer; Prior adjuvant fluorouracil for resected stage II-IV disease allowed if adjuvant therapy concluded at least 1 year before documentation of recurrent disease - Endocrine therapy: Not specified - Radiotherapy: See Disease Characteristics; At least 4 weeks since prior major radiotherapy (e.g., chest or bone palliative radiotherapy); No prior radiotherapy to more than 15% of bone marrow; No prior standard adjuvant radiotherapy for rectal cancer - Surgery: See Disease Characteristics; At least 4 weeks since prior major surgery (e.g., laparotomy) (2 weeks for minor surgery) and recovered; Insertion of a vascular access device not considered major or minor surgery - Other: No other concurrent investigational agents --Patient Characteristics-- - Age: 18 and over - Performance status: ECOG 0-2 - Life expectancy: At least 12 weeks - Hematopoietic: Absolute granulocyte count at least 1,500/mm3; Platelet count at least 100,000/mm3; Hemoglobin at least 9.0 g/dL (transfusion allowed) - Hepatic: Bilirubin no greater than 1.5 mg/dL; AST no greater than 5 times upper limit of normal (ULN); Alkaline phosphatase no greater than 5 times ULN - Renal: Creatinine no greater than 1.5 times ULN - Cardiovascular: No uncontrolled hypertension; No unstable angina; No symptomatic congestive heart failure; No myocardial infarction within the past 6 months; No serious uncontrolled arrhythmia; No New York Heart Association class III or IV cardiac disease - Pulmonary: No interstitial pneumonia or extensive and symptomatic interstitial fibrosis of the lung; No pleural effusion or ascites that cause respiratory compromise (grade 2 or worse dyspnea) - Other: Not pregnant or nursing; Negative pregnancy test; Fertile patients must use effective contraception; No active or uncontrolled infection; No symptomatic sensory peripheral neuropathy; No other prior or concurrent malignancy within the past 3 years except nonmelanoma skin cancer, carcinoma in situ of the uterine cervix, or other resected malignant tumor with less than a 10% probability of tumor relapse within 3 years of diagnosis; No medical or psychiatric conditions that would preclude study; No colonic or small bowel disorders with uncontrolled symptoms of more than 3 loose stools per day; Colostomy or ileostomy allowed at investigator's discretion
Total Enrollment:
Location and Contact Information:
Overall Study Official:
RichardGoldberg, Study Chair, North Central Cancer Treatment Group
Veterans Affairs Medical Center - West Los Angeles
Los Angeles, California, 90073
United States
Veterans Affairs Medical Center - Tucson
Tucson, Arizona, 85723
United States
Oncology & Hematology of Ottumwa, PC
Ottumwa, Iowa, 52501
United States
Saint Joseph Medical Center
Joliet, Illinois, 60435
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50309
United States
Rhode Island Hospital
Providence, Rhode Island, 02903
United States
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
United States
Hematology Oncology Associates of Illinois-Highland Park
Highland Park, Illinois, 60035
United States
Midwest Radiation Oncology Physicians
Peoria, Illinois, 61636
United States
Veterans Affairs Medical Center - Ann Arbor
Ann Arbor, Michigan, 48105
United States
Queen Elizabeth Hospital, PEI
Charlottetown, Prince Edward Island, C1A 8T5
Canada
St. Mary's Medical Center
Saginaw, Michigan, 48601
United States
Mayo Clinic Hospital
Phoenix, Arizona, 85054-4502
United States
Veterans Affairs Medical Center - San Francisco
San Francisco, California, 94121
United States
University of Wisconsin Comprehensive Cancer Center
Madison, Wisconsin, 53792-6164
United States
CCOP - Santa Rosa Memorial Hospital
Santa Rosa, California, 95403
United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213
United States
San Juan City Hospital
San Juan, , 00936-7344
Puerto Rico
St. Anthony's Memorial Hospital
Effingham, Illinois, 62401
United States
Lawrence Memorial Hospital of Medford/Hallmark Health Systems
Medford, Massachusetts, 02155
United States
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2
Canada
CCOP - Cancer Research for the Ozarks
Springfield, Missouri, 65807
United States
Saint Mary Regional Center
Langhorne, Pennsylvania, 19047
United States
Hematology Oncology Associates of Illinois - Lake Shore Dr
Chicago, Illinois, 60611
United States
Stanford University Medical Center
Stanford, California, 94305-5408
United States
InterCommunity Cancer Center of Western Illinois
Galesburg, Illinois, 61401
United States
Peoria Urological Associates
Peoria, Illinois, 61614
United States
Cancer Center of Kansas - Kingman
Kingman, Kansas, 67068
United States
MBCCOP - LSU Health Sciences Center
New Orleans, Louisiana, 70112
United States
Oncology Hematology West, P.C.
Omaha, Nebraska, 68114
United States
Moses Taylor Hospital
Scranton, Pennsylvania, 18510
United States
Alexandria Radiation Oncology
Alexandria, Minnesota, 56308
United States
CCOP - Metro-Minnesota
St. Louis Park, Minnesota, 55416
United States
Henry Ford Hospital
Detroit, Michigan, 48202
United States
Oncology/Hematology Associates of Central Illinois, P.C.
Peoria, Illinois, 61602
United States
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, 67801
United States
Veterans Affairs Outpatient Clinic - Martinez
Martinez, California, 94553
United States
Illinois Valley Community Hospital
Peru, Illinois, 61354
United States
Fairview University Medical Center - Riverside Campus
Minneapolis, Minnesota, 55454-1395
United States
University of Florida - Gainesville
Gainesville, Florida, 32610-0277
United States
Silver Cross Hospital
Joliet, Illinois, 60432
United States
Penrose Cancer Center
Colorado Springs, Colorado, 80933
United States
CCOP - Atlanta Regional
Atlanta, Georgia, 30342-1701
United States
Mercy Hospital and Medical Center
Chicago, Illinois, 60616
United States
Trillium Health Centre
Mississauga, Ontario, L5B 1B8
Canada
Veterans Affairs Medical Center - Atlanta (Decatur)
Decatur, Georgia, 30033
United States
Huntsman Cancer Institute
Salt Lake City, Utah, 84112
United States
Hematology/Oncology Associates of Illinois, LLC
Melrose Park, Illinois, 60160
United States
Northwestern Connecticut Oncology-Hematology Associates
Torrington, Connecticut, 06790
United States
Cancer Center of Kansas - Wichita
Wichita, Kansas, 67214
United States
Mercy Hospital
Coon Rapids, Minnesota, 55433
United States
Veterans Affairs Medical Center - Birmingham
Birmingham, Alabama, 35233-1996
United States
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, 48106
United States
St. John Hospital and Medical Center
Detroit, Michigan, 48236
United States
Veterans Affairs Medical Center - Columbia (Truman Memorial)
Columbia, Missouri, 65201
United States
Alegent Health-Midlands Community Hospital
Papillion, Nebraska, 68046-4194
United States
Cancer Center of Kansas - Newton
Newton, Kansas, 67114
United States
Veterans Affairs Medical Center - Madison
Madison, Wisconsin, 53705
United States
St. Mary-Corwin Regional Medical Center
Pueblo, Colorado, 81004
United States
Edward H. Kaplan MD and Associates
Skokie, Illinois, 60076
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314
United States
Veterans Affairs Medical Center - Jackson
Jackson, Mississippi, 39216
United States
Hematology-Oncology Associates of Illinois
Chicago, Illinois, 60611-2998
United States
Therapy Associates Hematology/Oncology
Evansville, Indiana, 47715
United States
Balcueva Clinic
Saginaw, Michigan, 48602
United States
Mendota Community Hospital
Mendota, Illinois, 61342
United States
Siouxland Hematology-Oncology
Sioux City, Iowa, 51101-1733
United States
Trinitas Hospital - Jersey Street Campus
Elizabeth, New Jersey, 07201
United States
CCOP - Columbia River Program
Portland, Oregon, 97213
United States
Cancer Center of Kansas - Winfield
Winfield, Kansas, 67156
United States
CCOP - Mount Sinai Medical Center
Miami, Florida, 33140
United States
Illinois Oncology Research Association
Peoria, Illinois, 61602
United States
St. John Macomb Hospital
Warren, Michigan, 48093-3494
United States
Keesler Medical Center - Keesler AFB
Keesler AFB, Mississippi, 39534-2576
United States
Madigan Army Medical Center
Tacoma, Washington, 98431-5000
United States
United Hospital
St. Paul, Minnesota, 55102
United States
North Coast Cancer Care, Inc.
Sandusky, Ohio, 44870
United States
University of Minnesota Cancer Center
Minneapolis, Minnesota, 55455
United States
St. Joseph's Hospital Medical Center
Bloomington, Illinois, 61701
United States
Alegent Health Southwest Iowa Medical Center
Council Bluffs, Iowa, 51503
United States
Fairview-Southdale Hospital
Edina, Minnesota, 55435
United States
British Columbia Cancer Agency
Vancouver, British Columbia, V5Z 4E6
Canada
Galesburg Clinic
Galesburg, Illinois, 61401
United States
Center for Cancer And Hematologic Disease
Cherry Hill, New Jersey, 08046
United States
Toledo Hospital
Toledo, Ohio, 43606
United States
Muhlenberg Hospital Center
Bethlehem, Pennsylvania, 18017
United States
Humber River Regional Hospital
Weston, Ontario, M9N 1N8
Canada
Mount Sinai Hospital - Toronto
Toronto, Ontario, M5G 1X5
Canada
St. Luke's Regional Medical Center
Sioux City, Iowa, 51104
United States
Veterans Affairs Medical Center - Palo Alto
Palo Alto, California, 94304
United States
Emory University Hospital - Atlanta
Atlanta, Georgia, 30322
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314
United States
CCOP - Upstate Carolina
Spartanburg, South Carolina, 29303
United States
Poudre Valley Radiation Oncology
Fort Collins, Colorado, 80528
United States
Magee-Womens Hospital
Pittsburgh, Pennsylvania, 15213-3180
United States
Veterans Affairs Medical Center - Memphis
Memphis, Tennessee, 38104
United States
CCOP - Marshfield Medical Research and Education Foundation
Marshfield, Wisconsin, 54449
United States
Mercy/Unity Hospitals
Fridley, Minnesota, 55432
United States
Vermont Cancer Center
Burlington, Vermont, 05401-3498
United States
Rice Memorial Hospital
Willmar, Minnesota, 56201
United States
Veterans Affairs Medical Center - Minneapolis
Minneapolis, Minnesota, 55417
United States
Carle Foundation Hospital
Urbana, Illinois, 61801
United States
St. Louis University Health Sciences Center
St. Louis, Missouri, 63110-0250
United States
Oklahoma Medical Research Foundation
Oklahoma City, Oklahoma, 73104
United States
Comprehensive Cancer Center at Wake Forest University
Winston Salem, North Carolina, 27157-1082
United States
Bismarck Cancer Center
Bismark, North Dakota, 58501-4445
United States
CCOP - Northwest
Tacoma, Washington, 98405-0986
United States
Barnes-Jewish Hospital
St. Louis, Missouri, 63110
United States
Trinity Medical Center
Moline, Illinois, 61265-1291
United States
Saint Luke's Hospital
Maumee, Ohio, 43537
United States
Veterans Affairs Medical Center - Kansas City
Kansas City, Missouri, 64128
United States
Luther Hospital
Eau Claire, Wisconsin, 54703
United States
Cancer Center and Beckman Research Institute, City of Hope
Duarte, California, 91010-3000
United States
Liberal Cancer Center of Kansas
Liberal, Kansas, 67901
United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007
United States
Porter Adventist Hospital
Denver, Colorado, 80210
United States
CCOP - Southeast Cancer Control Consortium
Winston Salem, North Carolina, 27104-4241
United States
MBCCOP - Massey Cancer Center
Richmond, Virginia, 23298-0037
United States
North Memorial Research Center
Minneapolis, Minnesota, 55442-2900
United States
NYU School of Medicine's Kaplan Comprehensive Cancer Center
New York City, New York, 10016
United States
Mount Sinai Medical Center, NY
New York City, New York, 10029
United States
Lancaster General Hospital
Lancaster, Pennsylvania, 17604-3555
United States
Veterans Affairs Medical Center - Wichita
Wichita, Kansas, 67218
United States
State University of New York - Upstate Medical University
Syracuse, New York, 13210
United States
Pasqua Hospital
Regina, Saskatchewan, S4T 7T1
Canada
Cancer Center of Kansas - Chanute
Chanute, Kansas, 66720
United States
St. Elizabeth Regional Medical Center
Lincoln, Nebraska, 68510
United States
British Columbia Cancer Agency - Centre for the Southern Interior
Kelowna, British Columbia, V1Y 5L3
Canada
South Jersey Regional Cancer Center
Millville, New Jersey, 08332
United States
Veterans Affairs Medical Center - Denver
Denver, Colorado, 80220
United States
Williamsburg Radiation Oncology Center
Lincoln, Nebraska, 68516
United States
Geisinger Wyoming Valley Medical Center
Wilkes Barre, Pennsylvania, 18711
United States
New York Presbyterian Hospital - Cornell Campus
New York City, New York, 10021
United States
British Columbia Cancer Agency - Vancouver Island Cancer Centre
Victoria, British Columbia, V8R 6V5
Canada
Grady Memorial Hospital
Atlanta, Georgia, 30335
United States
Riverview Medical Center - Booker Cancer Center
Red Bank, New Jersey, 07701
United States
Duke Comprehensive Cancer Center
Durham, North Carolina, 27710
United States
Brooke Army Medical Center
Fort Sam Houston, Texas, 78234
United States
MBCCOP - Gulf Coast
Mobile, Alabama, 36688
United States
Veterans Affairs Medical Center - Omaha
Omaha, Nebraska, 68105
United States
Hutchinson Area Health Care
Hutchinson, Minnesota, 55350
United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426
United States
Hopedale Medical Complex Hospital
Hopedale, Illinois, 61747
United States
Wood County Oncology Center
Bowling Green, Ohio, 43402
United States
Holy Family Medical Center
Des Plaines, Illinois, 60016
United States
Alexandria Clinic
Alexandria, Minnesota, 56308
United States
Bergan Mercy Medical Center
Omaha, Nebraska, 68124
United States
CCOP - Greenville
Greenville, South Carolina, 29615
United States
Bixby Medical Center
Adrian, Michigan, 49221
United States
North Shore Oncology Hematology Associates
Libertyville, Illinois, 60048
United States
CCOP - Bay Area Tumor Institute
Oakland, California, 94609-3305
United States
Presbyterian-St Luke's Medical Center
Denver, Colorado, 80218
United States
Veterans Affairs Medical Center - Lakeside Chicago
Chicago, Illinois, 60611
United States
St. Margaret's Hospital
Spring Valley, Illinois, 61362
United States
Jonsson Comprehensive Cancer Center, UCLA
Los Angeles, California, 90095-1781
United States
Veterans Affairs Medical Center - Hines (Hines Junior VA Hospital)
Hines, Illinois, 60141
United States
Fairview Ridges Hospital
Burnsville, Minnesota, 55337
United States
Southeast Nebreska Hematology-Oncology Consultants, PC
Lincoln, Nebraska, 68516
United States
Affiliated Urology Specialists
Peoria, Illinois, 61603
United States
St. James Hospital
Pontiac, Illinois, 61764
United States
Prairie View Clinic
Lincoln, Nebraska, 68506-5247
United States
Veterans Affairs Medical Center - Little Rock (McClellan)
Little Rock, Arkansas, 72205
United States
Mercy Medical Center
Cedar Rapids, Iowa, 52403
United States
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612-9497
United States
CCOP - Evanston
Evanston, Illinois, 60201
United States
CCOP - Kansas City
Kansas City, Missouri, 64131
United States
Southlake Regional Health Centre
Newmarket, Ontario, L3Y 2P9
Canada
Mary Imogene Bassett Hospital
Cooperstown, New York, 13326
United States
North West Ohio Oncology Center
Maumee, Ohio, 43537
United States
Ellis Fischel Cancer Center - Columbia
Columbia, Missouri, 65203
United States
CCOP - Southern Nevada Cancer Research Foundation
Las Vegas, Nevada, 89106
United States
Medical Oncology Centre of Rosebank
Johannesburg, , 2193
South Africa
Sarah D. Culbertson Memorial Hospital
Rushville, Illinois, 62681
United States
Cedar Rapids Oncology Associates
Cedar Rapids, Iowa, 52403
United States
Saint Anthony Regional Hospital
Carroll, Iowa, 51401
United States
Lawrence and Memorial Hospital
New London, Connecticut, 06320
United States
Alegent Health - Immanuel Medical Center
Omaha, Nebraska, 68122
United States
Rocky Mountain Cancer Centers - Northern Colorado
Fort Collins, Colorado, 80524-4038
United States
BroMenn Regional Medical Center
Normal, Illinois, 61761
United States
Pekin Hospital
Pekin, Illinois, 61554
United States
Albert B. Chandler Medical Center, University of Kentucky
Lexington, Kentucky, 40536-0084
United States
Sioux Valley Hospital
Sioux Falls, South Dakota, 57117
United States
USC/Norris Comprehensive Cancer Center and Hospital
Los Angeles, California, 90033-0804
United States
Baptist Regional Cancer Institute - Jacksonville
Jacksonville, Florida, 32207
United States
CCOP - Dayton
Kettering, Ohio, 45429
United States
Veterans Affairs Medical Center - Milwaukee (Zablocki)
Milwaukee, Wisconsin, 53295
United States
Bristol Hospital
Bristol, Connecticut, 06011-0977
United States
Louisiana State University Health Sciences Center - Shreveport
Shreveport, Louisiana, 71130-3932
United States
Community Cancer Center of Monroe
Monroe, Michigan, 48162
United States
St. John's Hospital
Maplewood, Minnesota, 55109
United States
Graham Hospital Association
Canton, Illinois, 61520
United States
Pottstown Memorial Regional Cancer Center
Pottstown, Pennsylvania, 19464
United States
David Grant Medical Center
Travis Air Force Base, California, 94535
United States
UPCI @ UPMC Lee Hospital
Johnstown, Pennsylvania, 15901
United States
Cancer Care Ontario-London Regional Cancer Centre
London, Ontario, N6A 4L6
Canada
Community Hospital of Ottawa
Ottawa, Illinois, 61350
United States
Southern Oncology-Hematology Associates, P.A.
Vineland, New Jersey, 08360
United States
UPMC Horizon
Greenville, Pennsylvania, 16125
United States
Mayo Clinic Scottsdale
Scottsdale, Arizona, 85259
United States
University of California Davis Medical Center
Sacramento, California, 95817
United States
HealthOne Rose Medical Center
Denver, Colorado, 80220
United States
Proctor Hospital
Peoria, Illinois, 61614
United States
William R. Bliss Cancer Center
Ames, Iowa, 50010
United States
Fergus Falls Medical Group
Fergus Falls, Minnesota, 56537
United States
Tulane University School of Medicine
New Orleans, Louisiana, 70112
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50309
United States
BroMenn Lifecare Center
Bloomington, Illinois, 61701-3081
United States
Mason District Hospital
Havana, Illinois, 62644
United States
Regions Hospital
St. Paul, Minnesota, 55101
United States
St. Francis Medical Center
Trenton, New Jersey, 08629
United States
Northeastern Ontario Regional Cancer Centre, Sudbury
Sudbury, Ontario, P3E 5J1
Canada
Northwestern Ontario Regional Cancer Centre, Thunder Bay
Thunder Bay, Ontario, P7A 7T1
Canada
Methodist Medical Center of Illinois
Peoria, Illinois, 61636
United States
Creighton University Cancer Center
Omaha, Nebraska, 68131-2197
United States
Altru Health Systems
Grand Forks, North Dakota, 58201
United States
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109-0752
United States
Fulton County Health Center
Wauseon, Ohio, 43567
United States
CCOP - Oklahoma
Tulsa, Oklahoma, 74136
United States
Central Mesabi Medical Center
Hibbing, Minnesota, 55746
United States
Fremont Memorial Hospital
Fremont, Ohio, 43420
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314
United States
Providence Hospital - Southfield
Southfield, Michigan, 48075-9975
United States
Kewanee Hospital
Kewanee, Illinois, 61443
United States
Oncology Institute of Greater Lafayette
Lafayette, Indiana, 47904
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50309
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50309
United States
Sparrow Regional Cancer Center
Lansing, Michigan, 48909
United States
Veterans Affairs Medical Center - Detroit
Detroit, Michigan, 48201-1932
United States
Iowa Methodist Medical Center
Des Moines, Iowa, 50309
United States
Cancer Center of Kansas - Wellington
Wellington, Kansas, 67152
United States
Arizona Cancer Center
Tucson, Arizona, 85724
United States
Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903
United States
Lehigh Valley Hospital
Allentown, Pennsylvania, 18103
United States
Lineberger Comprehensive Cancer Center, UNC
Chapel Hill, North Carolina, 27599-7295
United States
Veterans Affairs Medical Center - Durham
Durham, North Carolina, 27705
United States
Hinsdale Hematology Oncology Associates
Hinsdale, Illinois, 60521
United States
Radiation Oncology Center
Dodge City, Kansas, 67801
United States
University of Kansas Medical Center
Kansas City, Kansas, 66160-7357
United States
Community Cancer Center
Normal, Illinois, 61761
United States
Hematology Oncology Associates - Skokie
Skokie, Illinois, 60076
United States
Wedgewood Medical Center
Lincoln, Nebraska, 68510
United States
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, 54601
United States
University of Connecticut Health Center
Farmington, Connecticut, 06360-7106
United States
St. Joseph's Medical Center
Brainerd, Minnesota, 56401
United States
Swedish-American Health System
Rockford, Illinois, 61104-2315
United States
Veterans Affairs Medical Center - Boston (Jamaica Plain)
Jamaica Plain, Massachusetts, 02130
United States
CCOP - Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, 49503
United States
Meeker County Memorial Hospital
Lichfield, Minnesota, 55355
United States
Pratt Cancer Center of Kansas
Pratt, Kansas, 67124
United States
Park Nicollet Clinic
St. Louis Park, Minnesota, 55416
United States
Galesburg Cottage Hospital
Galesburg, Illinois, 61402
United States
University of Colorado Cancer Center
Denver, Colorado, 80010
United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198-3330
United States
Memorial Medical Center
Ashland, Wisconsin, 54806
United States
CCOP - Columbus
Columbus, Ohio, 43206
United States
University of Pennsylvania Cancer Center
Philadelphia, Pennsylvania, 19104-4283
United States
University of Florida Health Science Center - Jacksonville
Jacksonville, Florida, 32209
United States
Mayo Clinic
Jacksonville, Florida, 32224
United States
Duluth Clinic
Duluth, Minnesota, 55805
United States
Midwest Urological Group
Peoria, Illinois, 61603
United States
Ottumwa Regional Health Center
Ottumwa, Iowa, 52501
United States
Trinity Medical Center
Rock Island, Illinois, 61201
United States
Bryan LGH Medical Center East
Lincoln, Nebraska, 68506
United States
St. Boniface General Hospital
Winnipeg, Manitoba, R2H 2A6
Canada
Brainerd Medical Center
Brainerd, Minnesota, 56401
United States
Office of Susan Hansen, M.D.
Lincoln, Nebraska, 68506
United States
St. Joseph Hospital
Omaha, Nebraska, 68131-2197
United States
Memorial Sloan-Kettering Cancer Center
New York City, New York, 10021
United States
CCOP - St. Louis-Cape Girardeau
St. Louis, Missouri, 63141
United States
Veterans Affairs Medical Center - Lexington
Lexington, Kentucky, 40511-1093
United States
Miller-Dwan Medical Center
Duluth, Minnesota, 55805
United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57709
United States
McDonough District Hospital
Macomb, Illinois, 61455
United States
Comprehensive Cancer and Hematology Associates
Voorhees, New Jersey, 08043
United States
Veterans Affairs Medical Center - Buffalo
Buffalo, New York, 14215
United States
Lima Memorial Hospital
Lima, Ohio, 45804
United States
MCO Cancer Institute
Toledo, Ohio, 43614
United States
Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County
Mount Holly, New Jersey, 08060
United States
Midelfort Clinic
Eau Claire, Wisconsin, 54703
United States
Veterans Affairs Medical Center - Long Beach
Long Beach, California, 90822
United States
Joliet Oncology/Hematology Associates, Ltd.
Joliet, Illinois, 60435
United States
University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, 01655
United States
Firelands Regional Medical Center
Sandusky, Ohio, 44870
United States
Delaware County Memorial Hospital
Drexel Hill, Pennsylvania, 19026
United States
Medcenter One Health System
Bismark, North Dakota, 58501
United States
CCOP - Scott and White Hospital
Temple, Texas, 76508
United States
Meriter Hospital
Madison, Wisconsin, 53715
United States
Poudre Valley Hospital
Fort Collins, Colorado, 80524
United States
Centre Hospitalier de l'Universite de Montreal
Montreal, Quebec, H2L-4M1
Canada
Hahnemann University Hospital
Philadelphia, Pennsylvania, 19102-1192
United States
Robert H. Lurie Comprehensive Cancer Center, Northwestern University
Chicago, Illinois, 60611-3013
United States
Veterans Affairs Medical Center - San Juan
San Juan, , 00927-5800
Puerto Rico
Barrett Cancer Center, The University Hospital
Cincinnati, Ohio, 45267-0502
United States
Scranton Hematology-Oncology
Scranton, Pennsylvania, 18510
United States
University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78284-7811
United States
Veterans Affairs Medical Center - Temple
Temple, Texas, 76504
United States
Aultman Cancer Center
Canton, Ohio, 44710
United States
Veterans Affairs Medical Center - White River Junction
White River Junction, Vermont, 05009
United States
Wayne Memorial Hospital
Honesdale, Pennsylvania, 18431-1498
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314
United States
Mayo Clinic Cancer Center
Rochester, Minnesota, 55905
United States
Columbia Medical Center of Aurora North Campus
Aurora, Colorado, 80011
United States
Deerpath Medical Associates
Lake Forest, Illinois, 60045
United States
British Columbia Cancer Agency - Fraser Valley Cancer Centre
Surrey, British Columbia, V3V 1Z2
Canada
Herbert Irving Comprehensive Cancer Center
New York City, New York, 10032
United States
Central Pennsylvania Hematology and Medical Oncology Associates
Lemoyne, Pennsylvania, 17043
United States
Pretoria Academic Hospitals
Pretoria, , 0001
South Africa
Hunterdon Regional Cancer Center
Flemington, New Jersey, 08822
United States
Albert Einstein Cancer Center
Philadelphia, Pennsylvania, 19141
United States
Aurora Sinai Samaritan Medical Center
Milwaukee, Wisconsin, 53201-0342
United States
Healtheast Cancer Care
St. Paul, Minnesota, 55102
United States
Peterborough Oncology Clinic
Peterborough, Ontario, K9H 7B6
Canada
Altru Cancer Center
Grand Forks, North Dakota, 58206
United States
Morton Hospital & Medical Center
Taunton, Massachusetts, 02780
United States
New Britain General Hospital
New Britain, Connecticut, 06050
United States
CCOP - Christiana Care Health Services
Wilmington, Delaware, 19899
United States
Woman Wise Blanchard Valley Regional Health Center
Findlay, Ohio, 45840
United States
Geisinger Medical Group
State College, Pennsylvania, 16801
United States
Northwest Oncology and Hematology, S.C.
Elk Grove Village, Illinois, 60007
United States
Mercy Hospital Medical Center
Des Moines, Iowa, 50314
United States
Veterans Affairs Medical Center - Cincinnati
Cincinnati, Ohio, 45220-2288
United States
University of California San Diego Cancer Center
La Jolla, California, 92093-0658
United States
Associates in Women's Health - Wichita
Wichita, Kansas, 67208
United States
Nova Scotia Cancer Centre
Halifax, Nova Scotia, B3H 1V7
Canada
Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, 48201-1379
United States
Des Moines General Hospital
Des Moines, Iowa, 50309
United States
CentraCare Health Plaza
St. Cloud, Minnesota, 56303
United States
Albert Einstein Comprehensive Cancer Center
Bronx, New York, 10461
United States
Wichita Clinic Cancer Medicine Associates, P.A.
Wichita, Kansas, 67208
United States
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Canada
Conemaugh Memorial Hospital
Johnstown, Pennsylvania, 15905
United States
Community Hospital of the Monterey Peninsula
Monterey, California, 93940
United States
William W. Backus Hospital
Norwich, Connecticut, 06360
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50309
United States
Cancer Center of Kansas - Salina
Salina, Kansas, 67401
United States
Halstead Cancer Center of Kansas
Halstead, Kansas, 67056
United States
New England Medical Center Hospital
Boston, Massachusetts, 02111
United States
Radiation Therapy Center
Hibbing, Minnesota, 55746
United States
St. Joseph Hospital
Denver, Colorado, 80218
United States
St. Mary's/Duluth Clinic Health System
Duluth, Minnesota, 55805
United States
Meritcare Roger Maris Cancer Center
Fargo, North Dakota, 58122
United States
Veterans Affairs Medical Center - Portland
Portland, Oregon, 97207
United States
Maisonneuve-Rosemont Hospital
Montreal, Quebec, H1T 2M4
Canada
CCOP - Greater Phoenix
Phoenix, Arizona, 85006-2726
United States
Borgess Medical Center
Kalamazoo, Michigan, 49048-1666
United States
Oregon Cancer Center
Portland, Oregon, 97201-3098
United States
Saint Joseph's Health Centre - Toronto
Toronto, Ontario, M6R 1B5
Canada
Avera McKennan Hospital and University Health Center
Sioux Falls, South Dakota, 57105-1080
United States
Dean Medical Center
Madison, Wisconsin, 53715
United States
Nanaimo Cancer Clinic
Nanaimo, British Columbia, V9S 2B7
Canada
Fox Valley Hematology and Oncology
Appleton, Wisconsin, 54911
United States
Geisinger Medical Center
Danville, Pennsylvania, 17822-2001
United States
Via Christi Regional Medical Center
Wichita, Kansas, 67214
United States
Haematology-Oncology Associates, Inc.
Toledo, Ohio, 43623-4474
United States
Sioux Valley Clinic
Sioux Falls, South Dakota, 57104
United States
Hematology Oncology Associates of Illinois, LLC
Oak Park, Illinois, 60304
United States
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, 44195
United States
Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, 53066
United States
CHUM Hopital Saint-Luc
Montreal, Quebec, H2X 3J4
Canada
Veterans Affairs Medical Center - Phoenix (Hayden)
Phoenix, Arizona, 85012
United States
Trinity Medical Center
Rock Island, Illinois, 61201
United States
University of Chicago Cancer Research Center
Chicago, Illinois, 60637-1470
United States
Avera Cancer Institute
Sioux Falls, South Dakota, 57105
United States
St. Francis Hospital and Medical Center
Hartford, Connecticut, 06105
United States
Glenbrook Hospital
Glenview, Illinois, 60025
United States
Cancer Center of Kansas - Arkansas City
Arkansas City, Kansas, 67005
United States
Hematology Oncology Associates of the Quad Cities
Bettendorf, Iowa, 52722
United States
Veterans Affairs Medical Center - Syracuse
Syracuse, New York, 13210
United States
Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188
United States
Midwest Cancer Research Group, Inc.
Skokie, Illinois, 60077
United States
Office of E. Michael Lodish
Madison Heights, Michigan, 48071-3457
United States
St. Vincent Mercy Medical Center
Toledo, Ohio, 43608
United States
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
Canada
Memorial Hospital
Carthage, Illinois, 62321
United States
Marion Community Hospital
Carbondale, Pennsylvania, 18407
United States
Holden Comprehensive Cancer Center at The University of Iowa
Iowa City, Iowa, 52242-1009
United States
Burlington County Hematology Oncology Association, P.A.
Willingboro, New Jersey, 08046
United States
Pinnacle Health Hospitals
Harrisburg, Pennsylvania, 17105-8700
United States
Veterans Affairs Medical Center - Biloxi
Biloxi, Mississippi, 39531-2410
United States
DuBois Regional Medical Center
DuBois, Pennsylvania, 15801-0447
United States
Veterans Affairs Medical Center - Salt Lake City
Salt Lake City, Utah, 84148
United States
Veterans Affairs Medical Center - Richmond
Richmond, Virginia, 23249
United States
Franciscan Skemp Healthcare
La Crosse, Wisconsin, 54601-4796
United States
UCSF Cancer Center and Cancer Research Institute
San Francisco, California, 94143-0128
United States
Veterans Affairs Medical Center - Togus
Togus, Maine, 04330
United States
St. Rita's Medical Center
Lima, Ohio, 45801
United States
Mercy Medical Center - Sioux City
Sioux City, Iowa, 51101
United States
Ridgeview Medical Center
Waconia, Minnesota, 55387
United States
Swedish Medical Center
Englewood, Colorado, 80110
United States
Schneider Children's Hospital at North Shore
Manhasset, New York, 11030
United States
Eureka Hospital
Eureka, Illinois, 61530
United States
Loyola University Medical Center
Maywood, Illinois, 60153
United States
Iowa Lutheran Hospital
Des Moines, Iowa, 50316-2392
United States
St. Francis Medical Center
Peoria, Illinois, 61637
United States
Norris Cotton Cancer Center
Lebanon, New Hampshire, 03756-0002
United States
Boston Medical Center
Boston, Massachusetts, 02118
United States
St. Vincent Hospital
Green Bay, Wisconsin, 54307-3508
United States
Dwight David Eisenhower Army Medical Center
Fort Gordon, Georgia, 30905-5650
United States
CCOP - Merit Care Hospital
Fargo, North Dakota, 58122
United States
Akron City Hospital
Akron, Ohio, 44309
United States
CCOP - Central Illinois
Decatur, Illinois, 62526
United States
Chester County Hospital
West Chester, Pennsylvania, 19380
United States
University of Texas Medical Branch
Galveston, Texas, 77555-0209
United States
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.
Syracuse, New York, 13217
United States
Medical College of Ohio Hospital
Toledo, Ohio, 43614-0008
United States
Office of Sharon Cole, M.D.
Kenton, Ohio, 43326
United States
Ireland Cancer Center
Cleveland, Ohio, 44106-5065
United States
Hopital Charles Lemoyne
Greenfield Park, Quebec, J4V 2H1
Canada
Genesee Regional Medical Center
Flint, Michigan, 48503
United States
Veterans Affairs Medical Center - Shreveport
Shreveport, Louisiana, 71130
United States
St. Charles Hospital
Oregon, Ohio, 43616
United States
Mercy Hospital Cancer Center - Scranton
Scranton, Pennsylvania, 18501
United States
Anne Arundel Medical Center
Annapolis, Maryland, 21401
United States
Valley Cancer Center
Spring Valley, Illinois, 61362
United States
Latrobe Area Hospital
Latrobe, Pennsylvania, 15650
United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States
Burgess Health Center
Onawa, Iowa, 51040
United States
Dana-Farber Cancer Institute
Boston, Massachusetts, 02115
United States
CCOP - Virginia Mason Research Center
Seattle, Washington, 98101
United States
St. Alexius Medical Center
Bismark, North Dakota, 58502
United States
Morris Hospital
Morris, Illinois, 60450
United States
McFarland Clinic, P.C.
Ames, Iowa, 50010
United States
Duluth Clinic - Hibbing
Hibbing, Minnesota, 55746
United States
Bryan LGH Medical Center
Lincoln, Nebraska, 68502-3780
United States
Centro Mamografia Hospital Oncologico
Hato Rey, , 00919-1811
Puerto Rico
Hotel Dieu Health Sciences Hospital - Niagara
St. Catharines, Ontario, L2R 5K3
Canada
Chao Family Comprehensive Cancer Center
Orange, California, 92868
United States
Carle Cancer Center
Urbana, Illinois, 61801
United States
Veterans Affairs Medical Center - Chicago (Westside Hospital)
Chicago, Illinois, 60612
United States
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379
United States
Veterans Affairs Medical Center - Oklahoma City
Oklahoma City, Oklahoma, 73104
United States
Walter Reed Army Medical Center
Washington D.C., District of Columbia, 20307-5000
United States
Cancer Research Center of Hawaii
Honolulu, Hawaii, 96813
United States
CCOP - North Shore University Hospital
Manhasset, New York, 11030
United States
Veterans Affairs Medical Center - San Antonio (Murphy)
San Antonio, Texas, 78284
United States
Perry Memorial Hospital
Princeton, Illinois, 61356
United States
Hennepin County Medical Center - Minneapolis
Minneapolis, Minnesota, 55415
United States
University of Mississippi Medical Center
Jackson, Mississippi, 39216-4505
United States
MBCCOP - University of New Mexico HSC
Albuquerque, New Mexico, 87131
United States
Virginia Piper Cancer Institute
Minneapolis, Minnesota, 55407
United States
Armstrong County Memorial Hospital
Kittanning, Pennsylvania, 16201-8808
United States
Reading Hospital and Medical Center
Reading, Pennsylvania, 19612-6052
United States
UPMC/Passavant Hospital
Pittsburgh, Pennsylvania, 15237
United States
CCOP - Colorado Cancer Research Program, Inc.
Denver, Colorado, 80209-5031
United States
Algoma District Medical Group
Sault Sainte Marie, Ontario, P6B 1Y5
Canada
Mercy Cancer Center
Mason City, Iowa, 50401
United States
Mid Dakota Clinic, P.C.
Bismark, North Dakota, 58501
United States
Credit Valley Hospital
Mississauga, Ontario, L5M 2N1
Canada
Southeast Nebraska Hematology
Lincoln, Nebraska, 68516
United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314
United States
Veterans Affairs Medical Center - Albuquerque
Albuquerque, New Mexico, 87108-5138
United States
Flower Hospital - Pro Medica Health System
Sylvania, Ohio, 43560
United States
Lions Gate Hospital
North Vancouver, , V7L 2P9
Canada
Faulkner Hospital
Jamaica Plain, Massachusetts, 02130
United States
Rochester General Hospital
Rochester, New York, 14621
United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007
United States
Arthur G. James Cancer Hospital - Ohio State University
Columbus, Ohio, 43210-1240
United States
Riverside Hospital
Toledo, Ohio, 43604
United States
Veterans Affairs Medical Center - Dayton
Dayton, Ohio, 45428
United States
Swedish Cancer Institute
Seattle, Washington, 98104
United States
CCOP - Montana Cancer Consortium
Billings, Montana, 59101
United States
Fremont Area Medical Center
Fremont, Nebraska, 68025-2387
United States
Toledo Clinic, Inc.
Toledo, Ohio, 43623
United States
L'Hopital Laval
Ste Foy, Quebec, G1V 4G5
Canada
CCOP - Wichita
Wichita, Kansas, 67214-3882
United States
University of Tennessee, Memphis Cancer Center
Memphis, Tennessee, 38103
United States
Veterans Affairs Medical Center - New York
New York City, New York, 10010
United States
Mercy Ireland Cancer Center
Canton, Ohio, 44708
United States
Community Memorial Hospital
Missouri Valley, Iowa, 51555-1199
United States
Veterans Affairs Medical Center - Seattle
Seattle, Washington, 98108
United States
William Osler Health Centre
Brampton, Ontario, L6W 2Z8
Canada
UW Cancer Center Wausau Hospital
Wausau, Wisconsin, 54401
United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
United States
St. Luke's Hospital
Cedar Rapids, Iowa, 52406
United States
St. Cloud Hospital
St. Cloud, Minnesota, 56303
United States
Additional Information:
Study ID Numbers: CDR0000066665; NCCTG-N9741
Study Start Date: May 2001
Record last reviewed: September 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00003594
Other Recurrent Rectal Cancer Studies:
1. Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer
2. Chemotherapy, Radiation Therapy, and Surgery With or Without Epoetin alfa in Treating Patients With Resectable Rectal Cancer
3. Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed
4. Comparison of Adjuvant Chemotherapy Regimens in Treating Patients With Stage II or Stage III Rectal Cancer Who Are Receiving Radiation Therapy and Fluorouracil Before or After Surgery
5. Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Related Studies:
Other recurrent rectal cancer Clinical Trials
Other Nebraska Clinical Trials
Other Lincoln Clinical Trials
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
|
|
|
|
|
|
|
|
