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Home > "C" Clinical Trials Conditions > Clinical Investigation of Infections Due to Leishmanial Parasites  Clinical Investigation of Infections Due to Leishmanial Parasites
Clinical Investigation of Infections Due to Leishmanial Parasites
For Condition: Leishmaniasis,Leishmaniasis, Visceral
Status: Completed
Sponsor(s): National Institute of Allergy and Infectious Diseases (NIAID) ,
Synopsis: Mechanisms of host immune response to intracellular protozoa will be investigated in patients with naturally acquired infection employing a variety of in-vitro techniques. Both non-specific and antigen-specific humoral and cellular immune responses will be assessed. Parasites will be isolated from patients, cultivated in-vitro, and characterized. Responses to chemotherapy will be assessed parasitologically, immunologically and clinically.
Details: The main purpose of this protocol is to permit us to see patients who are referred to us for diagnosis and treatment of known or suspected leishmaniasis (from the Peace Corps, Smithsonian Institution, tourists, etc.). In the process of working up these patients, we sometimes encounter parasite isolates that are useful for research. We also can perform tests of cell-mediated immune function to evaluate how patients are responding to therapy. In addition, the protocol permits us to observe therapeutic responses to other drugs besides pentavalent antimony, if necessary.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Must be between the ages of 1 and 65 years.
Total Enrollment: 250
Location and Contact Information:
National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 790144; 79-I-0144
Study Start Date: December 17, 1979
Record last reviewed: February 1, 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001169
Other Leishmaniasis Studies:
1. Clinical Investigation of Infections Due to Leishmanial Parasites
Related Studies:
Other Leishmaniasis Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Clinical Investigation of Infections Due to Leishmanial Parasites
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