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Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS Clinical Trials Info presented on Clinical Trials Search is not intended to be a substitute for certified medical advice, visits or professional assistance using a real physician. We are not physicians. Always consult your dr. about Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS Clinical research trials and Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS health trials happen in many of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new drugs. The function of the studies / projects is to resolve particular human medical questions. Clinical trials are a popular manner for mDs, government agencies, and private sector corporations to discover remedies for all varieties of circumstances, like Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS. Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS Clinical Trials and other clinical trials allow volunteers to obtain healthcare treatment options before they are available to the masses. Some times the participants undergo professional assistance for free of charge, and occasionally they are paid for their time. Sometimes there is a cost for a Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS clinical trial. Human subjects often get the best healthcare available for their Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS condition. Dangers are a reality, however, and may include additional or frequent mD visits, healthcare dangers (potentially life-jeopardising), and/or the treatment being ineffectual. Trials are federally governed with rigorous guidelines to protect clinical trials patients.
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Home > "C" Clinical Trials Conditions > Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS  Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS
Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS
For Condition: Herpes Simplex,HIV Infections
Status: Completed
Sponsor(s): Gilead Sciences ,
Synopsis: The purpose of this study is to see if cidofovir gel (Forvade) is safe and effective in treating herpes simplex in patients with AIDS who do not respond to acyclovir.
Details: Patients receive open-label treatment with cidofovir gel.
Eligibility:
Study Type: Interventional, Treatment, Open Label
Minimum Age/Maximum Age: 13 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - AIDS diagnosis per CDC criteria. - At least partially external mucocutaneous HSV infection confirmed by culture of current outbreak. - Current HSV outbreak that is unresponsive to >= 10-day course of acyclovir at 1-4 gm/day po or 15 mg/kg/day IV or in vitro resistance of HSV isolate to acyclovir demonstrated within 60 days of study. - Signed, informed consent from parent or legal guardian for patients less than 18 years of age. Exclusion Criteria Co-existing Condition: Patients with the following conditions or symptoms are excluded: Evidence of cervical intraepithelial neoplasia class III (CIN III) on Pap smear (Pap smear required within 6 months of starting study drug). Concurrent Medication: Excluded: Acyclovir, valacyclovir, famciclovir, ganciclovir, foscarnet, topical trifluride, cidofovir injection or other systemic or topical drugs with anti-herpes activity. Required: >= 10 day course acyclovir at 1-4 gm/day po or 15mg/kg/day IV (not required if there is confirmed in vitro resistance to acyclovir).
Total Enrollment:
Location and Contact Information:
Sharp Mission Park / Med Group
Oceanside, California, 92054
United States
Mem Med Group Inc
Long Beach, California, 90806
United States
AIDS Healthcare Foundation Labs
Los Angeles, California, 90027
United States
Heywood Memorial Hosp
Gardner, Massachusetts, 01440
United States
Park Ctr for Health / Keith Vrhel
San Diego, California, 92103
United States
ID Associates
Dallas, Texas, 75231
United States
Christie Clinic / Urbana Campus
Urbana, Illinois, 61801
United States
Dr Susan M Diamond
Dallas, Texas, 75225
United States
Potrero Hill Med Ctr
San Francisco, California, 94107
United States
Central Texas Med Foundation
Austin, Texas, 78751
United States
Dr Nicholaos Bellos
Dallas, Texas, 75225
United States
Braude Mermin Spivey MD PC
Atlanta, Georgia, 30309
United States
Central Florida Research Initiative
Maitland, Florida, 32751
United States
Gouverneur Hosp
New York City, New York, 10002
United States
HIV Primary Care & Consult
Santa Rosa, California, 95404
United States
Additional Information:
Study ID Numbers: 218B; GS-96-307
Study Start Date:
Record last reviewed: November 1997
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002181
Other Hiv Infections Studies:
1. A Study of Rifabutin, Used Alone or with Ethambutol in the Prevention of Mycobacterium avium Complex (MAC) Bacteremia in Patients with AIDS
2. Pulmonary Complications of HIV Infection Study (PACS)
3. Use of a Test that Evaluates How the Body Handles Insulin and Glucose
4. Therapeutic Vaccination Followed by Treatment Interruption in HIV Infected Patients
5. Valganciclovir Prevention of Cytomegalovirus (CMV) Organ Damage
Related Studies:
Other HIV Infections Clinical Trials
Other Illinois Clinical Trials
Other Urbana Clinical Trials
Cidofovir as a Treatment for Herpes Simplex in Patients with AIDS
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