Search Clinical Trials
 
By Condition
 
By Location (USA)
 
By Location (Other)
 
By Sponsor
 
Resources
 
Privacy Policy
 
About Us
Disclaimer
Calcium and Bone Mass in Young Females Clinical Trials Information presented on Clinical Trials Search isn't designed to be a substitute for certified healthcare advice, travels to or professional assistance using a genuine medical doctor. We are not physicians. Always confer with your dr. about Calcium and Bone Mass in Young Females conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Calcium and Bone Mass in Young Females Clinical research trials and Calcium and Bone Mass in Young Females medical trials happen in hundreds of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectualness of new drugs. The intention of the studies / undertakings is to solve certain human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all forms of circumstances, such as Calcium and Bone Mass in Young Females. Calcium and Bone Mass in Young Females Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment choices before they are available to the general public. Some times the human subjects get treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Calcium and Bone Mass in Young Females clinical trial. Participants frequently get the best healthcare available for their Calcium and Bone Mass in Young Females condition. Risks are a reality, nonetheless, and can include extra or frequent physician trips, medical risks (possibly life-jeopardising), and/or the treatment being ineffective. Trials are federally governed with exacting guidelines to protect clinical trials subjects.

Home > "C" Clinical Trials Conditions > Calcium and Bone Mass in Young Females

Calcium and Bone Mass in Young Females



Calcium and Bone Mass in Young Females

For Condition: Osteoporosis
Status: Completed
Sponsor(s): National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) ,
Synopsis: We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls. At the start of this 7-year study, the average age of the girls was 11 years, and they had not yet reached puberty. The study will also provide information about the effect of calcium on body composition (body fat) and blood pressure in young women. We have been giving calcium to one group of participants in this study and giving a placebo (an inactive pill, or "sugar pill") to the other group. The results of this research will be important in preventing osteoporosis, because building more bone as a young person should reduce a woman's chances of developing osteoporosis later in life.
Details: This study evaluates the effect of calcium on bone mass accretion over 7 years in a cohort of 354 young females who were in pubertal Stage II at the start of the study. The average age of study participants at entry was 11 years; at the end of the study participants were 18 years old. The study looks at skeletal development under the influence of heredity, nutrition (calcium), and physical exercise. We gave calcium to participants in one arm of this clinical trial calcium. Participants in the other arm of the trial were given a placebo. The main outcome variable is the bone mass measured at different skeletal regions. The study will also provide data about the efficacy of calcium supplementation with regard to hypertension prevention and obesity. The results of this research will be important in preventing osteoporosis.
Eligibility:
Study Type:  Interventional, Prevention, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Bio-equivalence Study
Minimum Age/Maximum Age: 8 Years/13 Years
Genders: Female
Protocol Entry Criteria: Inclusion Criteria: - Pubertal stage II - Calcium intake below a threshold level - Caucasian - Normal health Exclusion Criteria: - Medications affecting calcium and bone metabolism - Chronic diseases - Metabolic bone disease - Abnormality in calcium metabolism
Total Enrollment: 354

Location and Contact Information:

Overall Study Official:
VelimirMatkovic,  Principal Investigator,  Ohio State University College of Medicine

OSU Bone and Mineral Metabolism Laboratory
Columbus,  Ohio,  43210
United States
 


Additional Information:
Study ID Numbers:  NIAMS-007;  R01 AR40736
Study Start Date: August 1991
Record last reviewed: February 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000402

Other Osteoporosis Studies:
1. Osteoporosis Prevention in Preadolescent Girls

2. Goserelin in Preventing Ovarian Failure in Women Receiving Adjuvant Chemotherapy for Breast Cancer

3. Effects of Parathyroid Hormone in Men with Osteoporosis

4. Parathyroid Hormone (PTH) with Alendronate for Osteoporosis

5. Adding Phosphorus to Osteoporosis Drug Treatment

Related Studies:

Other Osteoporosis Clinical Trials
Other Ohio Clinical Trials
Other Columbus Clinical Trials

Calcium and Bone Mass in Young Females
Modify your Search

  Other Osteoporosis Clinical Trials
  Other Ohio Clinical Trials
  Other Columbus Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103