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CAFE Comparison of Atypicals in First Episode



CAFE Comparison of Atypicals in First Episode

For Condition: Mental Disorders,Mental Health,Psychotic Disorders,Schizophrenia
Status: No longer recruiting
Sponsor(s): AstraZeneca , University of North Carolina
Synopsis: The purpose of this study is to compare the effectiveness, tolerability, and efficacy of the currently available atypical antipsychotic drugs olanzapine (2.5-20 mg/day), quetiapine (100-800 mg/day) and risperidone (0.5-4 mg/day) in patients with schizophrenia, schizophreniform disorder, or schizoaffective disorder who are experiencing their first psychotic episode.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 16 Years/40 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Patients must meet criteria for schizophreniform disorder, schizophrenia, or schizoaffective disorder with psychotic symptoms lasting 1-60 months - Psychotic symptoms must have persisted at least one month, and not more thn 5 years (60 months) - Patients must have no previous history of drug treatment (greater than a total of 16 weeks) with antipsychotics Exclusion Criteria: - Patients with history of psychotic disorder with recovery period of at least 3 months - Female patients who are pregnant or nursing - Patients with a known history of mental retardation
Total Enrollment: 

Location and Contact Information:

Research Site
Dallas,  Texas, 
United States
 


Additional Information:
Study ID Numbers:
  5077IL/0114; 
Study Start Date: 
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00034892

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