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Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6



Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6

For Condition: Heroin Dependence,Opioid-Related Disorders
Status: Terminated
Sponsor(s): National Institute on Drug Abuse (NIDA) , University of Colorado
Synopsis: to assess the abuse liability and examine the reinforcing effects of intravenous buprenorphine and buprenorphine/naloxone combinations in healthy, non-drug dependenct volunteers
Details: not available at this time
Eligibility:
Study Type:  Interventional, Treatment, Double-Blind, Placebo Control
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: Individuals must be healthy, non-drug dependent volunteers, be at least 18 years of age, and have no prior history of drug or alcohol abuse or dependence. Subjects must have had some minimal experience with opioids (e.g. at least two prior exposures) Exclusion Criteria: Individuals with evidence of an active DSM-IV Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g., liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.
Total Enrollment: 0

Location and Contact Information:

Overall Study Official:
LeslieAmass,  Principal Investigator,  University of Colorado

University of Colorado Health Sciences Center
Denver,  Colorado,  80206
United States
 


Additional Information:
Study ID Numbers:  NIDA-11160-6;  R01-11160-6
Study Start Date: 
Record last reviewed: December 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000331

Other Heroin Dependence Studies:
1. PK0496 Pharmacokinetics of Buprenorphine - 10

2. Treatment Efficacy for Drug Abuse and AIDS Prevention - 1

3. A Laboratory Model for Heroin Abuse Medications - 8

4. CS1008 A&B Eff/Safety trial of BUP/NX for the Treatment of Opiate Dependence - 1

5. Buprenorphine/Naloxone versus Clonidine For Out-patient Opiate Detoxification - 1

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Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6
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