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Buprenorphine Combination Tablet Feasibility - 1



Buprenorphine Combination Tablet Feasibility - 1

For Condition: Opioid-Related Disorders
Status: Completed
Sponsor(s): National Institute on Drug Abuse (NIDA) ,
Synopsis: 1) Determine target dose range of buprenorphine/naloxone combination tablet that provides therapeutic response in opiate addicts with low to moderate dependence. 2) Identify appropriate initial induction dose in opiate addicts with low to moderate dependence.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Double-Blind, Placebo Control
Minimum Age/Maximum Age: 21 Years/50 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: Males/Females ages 21-50, opiate dependence according to DSM-IV criteria, self-reported use within the last 30 days, agreeable to conditions of study and signed informed consent Exclusion Criteria: Psychiatric disorder that requires medication therapy, history of seizures, pregnant and/or nursing women, dependence on etoh or benzodiazepines or other sedative-hypnotics, acute hepatitis, other medical conditions that deem participation to be unsafe.
Total Enrollment: 0

Location and Contact Information:

Overall Study Official:
WalterLing,  Principal Investigator,  Friends Research Institute

Friends Research Institute
Los Angeles,  California,  90025
United States
 


Additional Information:
Study ID Numbers:
  NIDA-09260-1;  P50-09260-1
Study Start Date: August 1995
Record last reviewed: January 1996
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000298

Other Opioid-Related Disorders Studies:
1. PK 0396 - Buprenorphine Dose Escalation Trial - 2

2. Buprenorphine Combination Tablet Feasibility - 1

3. Buprenorphine Dosing Interval - 5

4. Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment 1(1) - 1

5. Neurobiology of Opioid Dependence: 1 - 1

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