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Home > "B" Clinical Trials Conditions > Bladder Cancer Case Control Study of Arsenic in Water  Bladder Cancer Case Control Study of Arsenic in Water
Bladder Cancer Case Control Study of Arsenic in Water
For Condition: Bladder Cancer
Status: Recruiting
Sponsor(s): National Institute of Environmental Health Sciences (NIEHS) ,
Synopsis: This study is examining the relationship between ingested arsenic and bladder cancer in two areas of California where a large percentage of the population was exposed to drinking water containing arsenic at low to moderate levels.
Details: Water supplies in many parts of the world contain naturally occurring arsenic. Previous studies have shown that arsenic at high doses can cause cancer of the bladder. The risk at lower doses is unknown. This study is examining the relationship between ingested arsenic and bladder cancer in central Nevada and Kings County, California, two areas where a large percentage of the population was exposed to drinking water containing arsenic at low to moderate levels. Approximately 200 people with bladder cancer and 400 people without bladder cancer will be included. Subjects are interviewed by telephone about past residences, occupations, diet, drinking water consumption, and other lifestyle factors. Arsenic measurements in well water have been collected from the appropriate state agencies and are being matched with residences and drinking water consumption rates to estimate lifetime arsenic exposures for each subject. People with bladder cancer will then be compared to those without to see if people with cancer were more likely to have lived in areas with arsenic in their drinking water.
Eligibility:
Study Type: Observational, Natural History, Longitudinal, Case Control, Retrospective Study
Minimum Age/Maximum Age: 20 Years/85 Years
Genders: Both
Protocol Entry Criteria: Cases must meet the following criteria: -Diagnosed with primary bladder cancer from January 1, 1997 until December 31, 2000. -Live in the following counties at the time of diagnosis: Churchill, Lyon, Mineral, Storey, Douglas, Carson City, Nevada, and Kings County, California -Ages 20-85 at the time of diagnosis. Controls will be matched to cases based on gender and five year age groups.
Total Enrollment: 600
Location and Contact Information:
Allan Smith Research Office *Recruiting*
Berkeley, California, 94720
United States
Recruiting Craig Steinmaus 510-843-1736
Additional Information:
Study ID Numbers: 7459-CP-001;
Study Start Date: October 1997
Record last reviewed: August 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00011518
Other Bladder Cancer Studies:
1. Nitrocamptothecin in Treating Patients With Metastatic Cancer of the Urinary Tract
2. Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium
3. Gefitinib Plus Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Bladder Cancer
4. Bladder Cancer Case Control Study of Arsenic in Water
5. Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney Function
Related Studies:
Other Bladder Cancer Clinical Trials
Other California Clinical Trials
Other Berkeley Clinical Trials
Bladder Cancer Case Control Study of Arsenic in Water
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