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Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft Nephropathy



Angiotensin-Converting Enzyme Gene Polymorphism and the Risk of Chronic Allograft Nephropathy

For Condition: Kidney Disease
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: This study is intended to help doctors learn about the relationships between specific genetic makeup (gene markers) and the development of chronic rejection. This study is being done to see if there is a relationship between genetic patterns and the development of Chronic Allograft Nephropathy (CAN). Medical scientists also hope to learn more about how genetic differences between people determine their response to a drug or a disease by storing a small blood sample in a special "bank". This sample may be tested at some point in the future in an attempt to better understand the factors that may influence rejection, transplantation outcomes and transplant success rates.
Details:
Eligibility:
Study Type:
  Observational, Natural History, Retrospective Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - All subjects must be recipients of a renal allograft. - Study subjects must have evidence of biopsy-proven Chronic Allograft Nephropathy (CAN). - Control subjects must not have evidence of CAN.
Total Enrollment: 

Location and Contact Information:

Univ. of Michigan Health System
Ann Arbor,  Michigan,  48109-0391,
United States
 


Additional Information:
Study ID Numbers:
  NCRR-M01RR00042-1678;  M01RR00042
Study Start Date: 
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00006328

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