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A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or treatment with a real dr.. We aren't doctors. Always consult your mD on A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. Clinical research trials and A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. medical trials occur in many of places across the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectiveness of new does drugs. The role of the studies / undertakings is to figure out certain human healthcare questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to locate treatments for all forms of circumstances, including A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis.. A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. Clinical Trials and other clinical trials permit volunteers to get medical treatment options before they are available to the masses. Most times the human subjects acquire treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. clinical trial. Participants oftentimes recieve the finest healthcare available for their A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis. condition. Dangers are a reality, nonetheless, and might include extra or frequent physician calls, health hazards (potentially life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.

Home > "A" Clinical Trials Conditions > A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis.

A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis.



A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis.

For Condition: Rheumatoid Arthritis
Status: Completed
Sponsor(s): Boehringer Ingelheim Pharmaceuticals ,
Synopsis: A 12-week trial consisting of 5 visits (6 if follow up is needed) to find out how effective and safe three different doses of meloxicam are compared with placebo in Rheumatoid Arthritis. Patient will take one dose of study medication daily.
Details: The primary aim of this trial is to compare the efficacy and safety of several doses of meloxicam (7.5 mg, 15 mg, and 22.5 mg) administered once daily with placebo over a period of 12 weeks in treatment of patients with RA. There will be 700 US patients enrolled and 500 US patients entered in 65-70 US sites.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Dose Comparison, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/80 Years
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: - Age greater than or equal to 18 and less than or equal to 80. - Diagnosis of Rheumatoid Arthritis for at least six weeks. - Taking an NSAID. - If female: using adequate contraception. - Willingness to stop current NSAID until criteria reached to begin study drug. - Able to provide written informed consent. EXCLUSION CRITERIA: - Intolerance or hypersensitivity to NSAIDs or ingredients of trial drug. - Pregnancy, lactating. - Use of investigational drug within 30 days prior to entering the trial. - History of peptic ulcer or of gastrointestinal hemorrhage except simple hemorrhoidal bleeding. - History of cerebrovascular or other bleeding disorder. - Severe hypertension. - Other disease that might interfere with safety of the patient or evaluation of trial drug (investigator’s opinion). - RA of functional class IV. - Synovectomy in any large joint within the past 6 months prior to entering the trial or planned during trial. - Concomitant therapy with anticoagulant, therapeutic doses of aspirin, phenothiazines, lithium, chronic GI-medication, analgesic drug (except acetaminophen up to 4 grams/day). - DMARDs initiated within past three months or dose changed less than two months before entering the trial. - Therapy with corticosteroids exceeding 10 mg/day prednisone equivalent or change in dose within 1 month before trial. - Concomitant therapy with ACTH within past month before entering the trial. - History of narcotic or alcohol abuse (past 12 months). - Abnormal laboratory values. - Previous participation in the present trial.
Total Enrollment: 

Location and Contact Information:

Westlake Medical Research, Inc.
Westlake Village,  California,  91361
United States
 

Scott Toder, MD
Johnston,  Rhode Island,  02919
United States
 

SW Florida Clinical Research Center
Tampa,  Florida,  33609
United States
 

Arthritis Associates Inc.
Orlando,  Florida,  32804
United States
 

Advanced Clinical Therapeutics, LLC (ACT)
Anchorage,  Alaska,  99508
United States
 

Altoona Center for Clinical Research
Duncansville,  Pennsylvania,  16635
United States
 

NTouch Research
St. Petersburg,  Florida,  33710
United States
 

Florida Medical Research Institute PA
Gainesville,  Florida,  32607
United States
 

Healthcard Research Consultants
Tulsa,  Oklahoma,  74135
United States
 

Radiant Research
Stuart,  Florida,  34996
United States
 

The Arthritis Center
Springfield,  Illinois,  62704
United States
 

Radiant Research Dallas
Dallas,  Texas,  75235
United States
 

Arthritis Northwest
Seattle,  Washington,  98166
United States
 

Arthritis Center of Texas
Dallas,  Texas,  75246-1632
United States
 

Phase III Clinical Research
Fall River,  Massachusetts,  02720
United States
 

Florida Medical Clinic, PA Clinical Research Division
Zephyrhills,  Florida,  33540
United States
 

DMI Health Care
Largo,  Florida,  33773
United States
 

NCCR
Chicago,  Illinois,  60611
United States
 

The Center for Rheumatology and Bone Research
Wheaton,  Maryland,  20902
United States
 

The Arthritis and Osteoporosis Center
Orangeburg,  North Carolina,  29118
United States
 

San Antonio Center for Clinical Research
San Antonio,  Texas,  78217
United States
 

Sarasota Arthritis Center
Sarasota,  Florida,  34239
United States
 

St. Louis Center for Clinical Research
St. Louis,  Missouri,  63141
United States
 

Pacific Arthritis Center Medical Group
Santa Maria,  California,  93454
United States
 

Alan Brodsky, M.D.
Dallas,  Texas,  75225
United States
 

Arthritis Regional Research Center
Mercerville,  New Jersey,  08619
United States
 

Clinical Trials, N.W.
Yakima,  Washington,  98902
United States
 

Sun Valley Arthritis Center, Ltd.
Glendale,  Arizona,  85308
United States
 

Metropolitan Clinical Research
Falls Church,  Virginia,  22044
United States
 

Low Country Research
North Charleston,  South Carolina,  29406
United States
 

Boling Clinical Trials
Rancho Cucamonga,  California,  91730
United States
 

Rheumatology, PC
Kalamazoo,  Michigan,  49009
United States
 

Indiana University Medical Center, Dept. of Medicine
Indianapolis,  Indiana,  46202
United States
 

East Bay Rheumatology Medical Group
San Leandro,  California,  94578
United States
 

Arthritis Associates Clinical Research of So. Florida
Delray Beach,  Florida,  33484
United States
 

Walter F. Chase, M.D. PA
Austin,  Texas,  78705
United States
 

The Wallace Rheumatic Study Center
Los Angeles,  California,  90048
United States
 

Arthritis Associates of Colorado Springs
Colorado Springs,  Colorado,  80910
United States
 

Irene Tong, M.D.
Pasadena,  California,  91105
United States
 

Rheumatology Assoc. of North Alabama
Huntsville,  Alabama,  35801
United States
 

Institute of Arthritis Research
Idaho Falls,  Idaho,  83404
United States
 

Clinical Research Center of CT/NY
Danbury,  Connecticut,  06810
United States
 

Arthritis and Rehab Center of Jacksonville, Inc.
Jacksonville,  Florida,  32204
United States
 

Columbia Arthritis Center
Columbia,  South Carolina,  29204
United States
 

Advances in Medicine
Rancho Mirage,  California,  92270
United States
 

Arthritis and Osteoporosis Assoc.
Lubbock,  Texas,  79410
United States
 

North Shore Rheumatology
Lake Forest,  Illinois,  60045
United States
 

Rheumatology and Arthritis Associates
Medford,  New Jersey,  08055
United States
 

Wendt Bristol Research Center
Columbus,  Ohio,  43214
United States
 

Renstar Medical Research
Ocala,  Florida,  34471
United States
 

The Center for Arthritis and Rheumatic Disease
Miami,  Florida,  33143
United States
 

Arthritis Center of Nebraska
Lincoln,  Nebraska,  68506
United States
 

Internal Medicine
Camp Hill,  Pennsylvania,  17011
United States
 

The Center for Rheumatology and Bone Research
Washington D.C.,  District of Columbia,  20006
United States
 

Clinical Research of Tampa Bay
Safety Harbor,  Florida,  34695
United States
 

Arthritis Consultants, Inc.
St. Louis,  Missouri,  63141
United States
 

Phoenix Center for Clinical Research
Phoenix,  Arizona,  85015
United States
 

Rheumatology Associates of Central Florida
Orlando,  Florida,  32806
United States
 

San Diego Arthritis & Osteoporosis Medical Clinic
San Diego,  California,  92120
United States
 

Tampa Medical Group Research
Tampa,  Florida,  33614
United States
 

Heartland Research Associates, LLC
Wichita,  Kansas,  67207
United States
 

Miami Research Associates
Miami,  Florida,  33173
United States
 

Coeur d'Alene Arthritis Clinical Trials
Coeur D Alene,  Idaho,  83814
United States
 

Miami Research Associates
Miami,  Florida,  33173
United States
 

Physician's Pharmaceutical Study Services
Everett,  Washington,  98201
United States
 

Rockford Clinic
Rockford,  Illinois,  60045
United States
 

Stephen Bookbinder, M.D.
Ocala,  Florida,  03474
United States
 

Hospital for Special Surgery
New York City,  New York,  10021
United States
 

Central Pennsylvania Clinical Research
Mechanicsburg,  Pennsylvania,  17055
United States
 

C.a.R.E
Erie,  Pennsylvania,  16508
United States
 

Arthritis Center of Reno
Reno,  Nevada,  89502
United States
 

Radiant Research
San Diego,  California,  92108
United States
 


Additional Information:
Study ID Numbers:
  BI 107.258; 
Study Start Date: July 2002
Record last reviewed: September 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00042068

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A multi-center trial to compare the efficacy and safety of three doses of Meloxicam and placebo in patients with Rheumatoid Arthritis.

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