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A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment by using a genuine medical doctor. We aren't mDs. Always confer with your doctor on A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs Clinical research trials and A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs healthcare trials occur in a lot of of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectivity of new does drugs. The role of the studies / undertakings is to solve specific human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to find treatments for all kinds of conditions, including A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs. A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs Clinical Trials and other clinical trials allow for volunteers to access health treatment choices before they are available to the general public. Many times the test subjects get treatment for without cost, and sometimes they are compensated for their time. Occasionally there is a cost for a A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs clinical trial. Test subjects typically receive the most effective healthcare possible for their A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs condition. Risks are a reality, nonetheless, and could include extra or frequent dr. calls, health hazards (perhaps life-jeopardizing), and/or the treatment being ineffective. Trials are federally regulated with rigid guidelines to protect clinical trials subjects.
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Home > "A" Clinical Trials Conditions > A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
For Condition: HIV Infections
Status: No longer recruiting
Sponsor(s): Triangle Pharmaceuticals ,
Synopsis: The purpose of this study is to compare the safety and effectiveness of emtricitabine and stavudine when given with didanosine plus efavirenz to HIV-infected patients.
Details:
Eligibility:
Study Type: Interventional, Treatment, Double-Blind, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients may be eligible for this study if they: - Are at least 18 years old at the time of screening. - Have plasma HIV-1 RNA loads (level of HIV in your blood) of 5,000 or more copies/ml at the time of screening. - Have not used any anti-HIV therapy for more than 2 days. - Have a negative pregnancy test within 22 days of starting study drugs. - Can be reached by telephone. Exclusion Criteria Patients will not be eligible for this study if they: - Are pregnant or breast-feeding. - Use alcohol or illegal drugs that, in the opinion of the principal investigator, may interfere with the patient's ability to follow the dosing schedule and protocol evaluations. - Are being treated for active tuberculosis. - Are using astemizole, cisapride, midazolam, triazolam, ergot derivatives, St. John's wort, or drugs for a mental disorder. - Have a history of a serious mental disorder. - Are unwilling to use an effective barrier method of birth control during the study (for women who can get pregnant). - Have a history of opportunistic infections and cancers (Mycobacterium avium complex, cytomegalovirus, toxoplasmic encephalitis or disseminated toxoplasmosis, cryptosporidiosis, Isospora belli, progressive multifocal leukoencephalopathy, visceral Kaposi's sarcoma, and lymphoma). Patients with past episode of pulmonary tuberculosis, Pneumocystis carinii pneumonia, or isolated cutaneous Kaposi's sarcoma are allowed. Medication for the prevention of PCP (TMP/SMX, nebulized pentamidine, and atovaquone) is allowed. - Have peripheral neuropathy (a painful condition affecting the nervous system) or history of peripheral neuropathy. - Cannot take medicine by mouth or have severe chronic diarrhea within 30 days before beginning the study. - Cannot eat 1 or more meals a day because of chronic nausea, vomiting, or abdominal or esophageal discomfort. - Have had a serious illness or injury within 30 days of screening. Treatment must have been completed for 14 days prior to study entry. - Have a history of AIDS-defining opportunistic infection, except for tuberculosis or infection of the stomach or intestines.
Total Enrollment:
Location and Contact Information:
Amelia Ct Clinic
Dallas, Texas, 75235
United States
FUNCEI
Buenos Aires, ,
Argentina
Northstar Med Clinic
Chicago, Illinois, 60657
United States
South Jersey Infectious Diseases Inc
Somers Point, New Jersey, 08244
United States
Fanno Creek Clinic
Portland, Oregon, 97219
United States
San Juan Veterans Administration Med Ctr
San Juan, , 009275800
Puerto Rico
Mem Med Group Inc
Long Beach, California, 90806
United States
Coastal Carolina Research Ctr
Mount Pleasant, South Carolina, 29464
United States
Erie County Med Ctr
Buffalo, New York, 14215
United States
Centre De Recherche En Infectiologie
Ste Foy, Quebec,
Canada
St Lukes Medical Group
San Diego, California, 92101
United States
Infectious Disease Specialists of Atlanta
Decatur, Georgia, 30033
United States
Beacon Clinic / Boulder Community Hosp
Boulder, Colorado, 80304
United States
Infectious Disease Research Inst
Tampa, Florida, 33614
United States
Gary Richmond MD
Ft. Lauderdale, Florida, 33316
United States
East Bay Clinical Trial Ctr
Concord, California, 94520
United States
Mount Sinai School of Medicine
New York City, New York, 10029
United States
Paragon Clinical Research
Cranston, Rhode Island, 02920
United States
Diversified Med Practices, PA
Houston, Texas, 77027
United States
Institute of Human Virology
Baltimore, Maryland, 21201
United States
Central Texas Clinical Research
Austin, Texas, 78705
United States
Albert Einstein College of Medicine
Bronx, New York, 10461
United States
Liberty Medical / Cabrini Hospital / Dept of Infec Diseases
New York City, New York, 10003
United States
Davies Med Ctr
San Francisco, California, 94114
United States
Howard Grossman
New York City, New York, 10011
United States
Robert Smith Medical Group
San Diego, California, 92103
United States
Health Positive
Safety Harbor, Florida, 34695
United States
Harbin Clinic
Rome, Georgia, 30165
United States
East Bay AIDS Ctr
Berkeley, California, 94705
United States
George Washington Univ Med Ctr
Washington D.C., District of Columbia, 20037
United States
Fenway Community Health Ctr
Boston, Massachusetts, 02115
United States
Abbott-Northwestern Hosp / Clinic 42
Minneapolis, Minnesota, 55404
United States
Viridae Clinical Sciences / University of British Columbia
Vancouver, British Columbia,
Canada
Swedish Med Ctr / Dr Peter Shalit
Seattle, Washington, 98104
United States
New England Med Ctr
Boston, Massachusetts, 02111
United States
Larry Bush
Palm Springs, Florida, 33461
United States
Nelson Tebedo Health Resource Ctr
Dallas, Texas, 75219
United States
Univ of Colorado Health Ctr / Denver Gen Hosp
Denver, Colorado, 80262
United States
North Shore Univ Hosp / Div of Infectious Diseases
Manhasset, New York, 11030
United States
Physicans Home Service
Washington D.C., District of Columbia, 20037
United States
Blick Med Associates
Stamford, Connecticut, 06901
United States
Hospital de Agudos JM Ramos Mejia
Buenos Aires, ,
Argentina
Tulane Univ Med Ctr / Infectious Diseases Sect
New Orleans, Louisiana, 70112
United States
Hospital Muniz
Buenos Aires, ,
Argentina
Hillsborough County Health Department
Tampa, Florida, 33602
United States
Fundacion HUES
Buenos Aires, ,
Argentina
Walter Gaman
Irving, Texas, 75038
United States
McMaster Univ Med Centre
Hamilton, Ontario,
Canada
Infectious Diseases Associates
Sarasota, Florida, 34239
United States
Wohlfeiler, Piperator & King, MD, PA
Miami, Florida, 33139
United States
AIDS Healthcare Foundation
Los Angeles, California, 90027
United States
Hospital Interzonal Gen de Agudos Oscar Alende
Mar del Plata, ,
Argentina
Univ of Alabama at Birmingham
Birmingham, Alabama, 352942050
United States
Univ TX Galveston Med Branch
Galveston, Texas, 77555
United States
Montreal Gen Hosp
Montreal, Quebec,
Canada
Dr Lawrence Fontana
New York City, New York, 10003
United States
Ingenix Kern McNeill Decatur
Atlanta, Georgia, 30309
United States
Instituto Nacional de la Nutricion
Mexico City, ,
Mexico
Orange Coast Med Group
Newport Beach, California, 92663
United States
Fundacion Arriaran
Santiago, ,
Chile
Saint Francis Mem Hosp / HIV Care
San Francisco, California, 94109
United States
South Miami Hosp
Miami, Florida, 33143
United States
Houston Clinical Research Network
Houston, Texas, 77006
United States
Additional Information:
Study ID Numbers: 298C; FTC-301
Study Start Date: August 2000
Record last reviewed: June 2006
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00006208
Other Hiv Infections Studies:
1. A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV (vCP205) and HIV-1 SF-2 rgp120 in HIV-1 Uninfected Adult Volunteers
2. Treatment of Hepatitis C in Hemophilic Patients with HIV
3. Effects of Storage on Lactate in Blood Samples
4. A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
5. Pharmacokinetics of Intermittent Rifabutin and Isoniazid with Daily Efavirenz
Related Studies:
Other HIV Infections Clinical Trials
Other California Clinical Trials
Other Newport Beach Clinical Trials
A Comparison of Emtricitabine and Stavudine Used with Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
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